MULTISTAGE DELIVERY OF ACTIVE AGENTS

MAURO FERRARI (Inventor), ENNIO TASCIOTTI (Inventor), JASON SAKAMOTO (Inventor)

Research output: Patent

Abstract

Multistage delivery vehicles are disclosed which include a first stage particle and a second stage particle. The first stage particle is a micro or nanoparticle that contains the second stage particle. The second stage particle includes an active agent, such as a therapeutic agent or an imaging agent. The multistage delivery vehicle allows sequential overcoming or bypassing of biological barriers. The multistage delivery vehicle is administered as a part of a composition that includes a plurality of the vehicles. Methods of making the multistage delivery vehicles are also provided.

Original languageEnglish (US)
Patent numberUS2016051481
IPCA61K 31/ 7088 A I
Priority date5/29/15
StatePublished - Feb 25 2016

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