Abstract
Multistage delivery vehicles are disclosed which include a first stage particle and a second stage particle. The first stage particle is a micro or nanoparticle that contains the second stage particle. The second stage particle includes an active agent, such as a therapeutic agent or an imaging agent. The multistage delivery vehicle allows sequential overcoming or bypassing of biological barriers. The multistage delivery vehicle is administered as a part of a composition that includes a plurality of the vehicles. Methods of making the multistage delivery vehicles are also provided.
| Original language | English (US) |
|---|---|
| Patent number | US2016051481 |
| IPC | A61K 31/ 7088 A I |
| Priority date | 5/29/15 |
| State | Published - Feb 25 2016 |