@article{3ac9a35144194442a5908c1975a4521e,
title = "Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida",
abstract = "In the United States, vanB-mediated resistance in enterococci is rare. We characterized three sequence type (ST) 6, vancomycin-resistant Enterococcus faecalis isolates causing bacteremia in unique patients in spatiotemporally distinct settings. Isolates were recovered between 2018 and 2020 in two cities in the United States (Houston, TX; Miami, FL). The isolates harbored the vanB operon on a chromosomally located Tn1549 transposon, and epidemiological data suggested multiple introductions of the vanB gene cluster into ST6 E. faecalis.",
keywords = "Enterococcus, VRE, antimicrobial resistance",
author = "Simar, {Shelby R.} and Tran, {Truc T.} and Rydell, {Kirsten B.} and Diana Panesso and Contreras, {German A.} and Munita, {Jose M.} and Cifuentes, {Renzo O.} and Abbo, {Lilian M.} and Pranoti Sahasrabhojane and Dinh, {An Q.} and Axell-House, {Dierdre B.} and Tor Savidge and Samuel Shelburne and Hanson, {Blake M.} and Arias, {Cesar A.}",
note = "Funding Information: Copyright {\textcopyright} 2022 American Society for Microbiology. All Rights Reserved. Address correspondence to Cesar A. Arias, CAArias@houstonmethodist.org, or Blake M. Hanson, Blake.Hanson@uth.tmc.edu. The authors declare a conflict of interest. C.A.A. has received grant support from MeMed Diagnostics, Merck Pharmaceuticals, and Entasis Pharmaceuticals. Received 21 September 2022 Returned for modification 25 October 2022 Accepted 1 December 2022 Published 21 December 2022 Funding Information: This work was supported by the National Institute of Allergy and Infectious Diseases (NIAID) K24AI121296, R01AI134637, R01AI148342-01, P01AI152999-01 to C.A.A. S.R.S. was partially funded under National Institutes of Health (NIH) pre-doctoral training grant (5T32AI055449-15 to Theresa M. Koehler/Michael Lorenz). B.M.H. was supported by NIAID K01AI148593-01 and P01AI152999-01. Publisher Copyright: {\textcopyright} 2022 American Society for Microbiology. All Rights Reserved.",
year = "2023",
month = jan,
doi = "10.1128/aac.01284-22",
language = "English (US)",
volume = "67",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "1",
}