@inbook{d3af9fdfea0845b4985217baa73161f3,
title = "Multiscale models for transport and biodistribution of therapeutics in cancer",
abstract = "The chapter discusses the computational framework dedicated to simulate time-dependent biodistribution with focus on cancer. While systemic pharmacokinetic and biodistribution problems are extensively studied, the factors considered here are drug transport from drug vectors, drug transport and biodistribution in the tumor microenvironment, whole organ, and including the biodistribution effect on tumor growth. Continuum-based computational strategies are presented. Selected example solutions demonstrate the applicability of this methodology to in vitro and in vivo conditions.",
keywords = "Convection, Diffusion, Doxorubicin, Finite element method, Molecular dynamics, Pharmacokinetics, Tumor microenvironment",
author = "Arturas Ziemys and Milos Kojic and Miljan Milosevic and Bernhard Schrefler and Mauro Ferrari",
year = "2018",
month = jan,
day = "1",
doi = "10.1016/B978-0-444-63964-6.00007-6",
language = "English (US)",
isbn = "9780444639646",
series = "Computer Aided Chemical Engineering",
publisher = "Elsevier B.V.",
pages = "209--237",
editor = "Davide Manca",
booktitle = "Computer Aided Chemical Engineering",
}