TY - JOUR
T1 - Multiple giant coronary artery aneurysms
T2 - A case report
AU - Al Salihi, S.
AU - Jacobi, Elizabeth M.
AU - Hunter, R.
AU - Buja, M.
N1 - Funding Information:
This article was supported by Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, Houston, Texas.
Publisher Copyright:
© 2016 Elsevier Inc. All rights reserved.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/5
Y1 - 2016/5
N2 - Background Coronary artery aneurysm is defined as a localized area of dilatation exceeding the diameter of the adjacent normal arterial segment by 50%. Giant aneurysms are those aneurysms that measure greater than 2 cm in diameter. There have been many pathologic diseases, including atherosclerosis, that have been implicated in the development of coronary artery aneurysms. Materials and methods We report a case of a 61-year-old African American male with multiple comorbidities including hypertension, congestive heart failure, abdominal aortic aneurysm, and bilateral iliac aneurysms, who was admitted to our hospital with exacerbation of congestive heart failure. Less than 2 weeks after admission, the patient suffered cardiac arrest while receiving dialysis and was unresponsive to resuscitative measures. Findings Autopsy was performed and revealed significant cardiomyopathy and giant coronary artery aneurysms involving the left anterior descending, left circumflex, and right coronary arteries. Both ventricles showed hypertrophy and dilation with multifocal areas of chronic myocardial scarring. Conclusions Coronary artery aneurysms and giant coronary artery aneurysms are an uncommon. As there are few reported cases in the literature, the cause, detection, and treatment of this disease are still largely unknown.
AB - Background Coronary artery aneurysm is defined as a localized area of dilatation exceeding the diameter of the adjacent normal arterial segment by 50%. Giant aneurysms are those aneurysms that measure greater than 2 cm in diameter. There have been many pathologic diseases, including atherosclerosis, that have been implicated in the development of coronary artery aneurysms. Materials and methods We report a case of a 61-year-old African American male with multiple comorbidities including hypertension, congestive heart failure, abdominal aortic aneurysm, and bilateral iliac aneurysms, who was admitted to our hospital with exacerbation of congestive heart failure. Less than 2 weeks after admission, the patient suffered cardiac arrest while receiving dialysis and was unresponsive to resuscitative measures. Findings Autopsy was performed and revealed significant cardiomyopathy and giant coronary artery aneurysms involving the left anterior descending, left circumflex, and right coronary arteries. Both ventricles showed hypertrophy and dilation with multifocal areas of chronic myocardial scarring. Conclusions Coronary artery aneurysms and giant coronary artery aneurysms are an uncommon. As there are few reported cases in the literature, the cause, detection, and treatment of this disease are still largely unknown.
KW - Case report
KW - Coronary artery aneurysm
KW - Giant aneurysms
KW - Multiple aneurysms
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U2 - 10.1016/j.carpath.2016.01.001
DO - 10.1016/j.carpath.2016.01.001
M3 - Article
C2 - 26878103
AN - SCOPUS:84962092466
SN - 1054-8807
VL - 25
SP - 203
EP - 207
JO - Cardiovascular Pathology
JF - Cardiovascular Pathology
IS - 3
ER -