Multifunctional nanoparticle systems for combined chemoand photothermal cancer therapy

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Hyperthermia has long been considered as an adjuvant therapy for treating various diseases. Cancer treatment exploiting hyperthermia shows great clinical potential for a wide range of tumors. Importantly, the efficacy of hyperthermal therapy has recently been enhanced by the development of functional nanomaterials. The unique physicochemical properties of nanomaterials afford the specific localization of hyperthermia to primary tumors and early-stage cancers. In particular, due to their high rate of light-to-heat conversion and their capacity to be activated by tissue-penetrating electromagnetic radiation, near-infrared (NIR) light-absorbing plasmonic nanomaterials have attracted considerable attention as candidates for noninvasive photothermal therapy. The purpose of this article is to provide a overview on the current development in multifunctional nanomaterials capable of combined hyperthermia-chemotherapy delivery.

Original languageEnglish (US)
Pages (from-to)118-128
Number of pages11
JournalFrontiers of Materials Science
Volume7
Issue number2
DOIs
StatePublished - Jun 2013

Keywords

  • combination therapy
  • drug delivery
  • hyperthermia
  • multifunctional nanoparticle
  • photothermal therapy

ASJC Scopus subject areas

  • Materials Science(all)

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