Multicystic adenomatoid hamartoma of the pancreas: A hitherto undescribed pancreatic tumor occurring in a 3-year-old boy

Michael J. Thrall, Jose Jessurun, Edward B. Stelow, N. Volkan Adsay, Selwyn M. Vickers, Amy K. Whitson, Daniel A. Saltzman, Stefan E. Pambuccian

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

This report describes an unusual pancreatic tumor in a 3-year-old boy. He presented with abdominal pain secondary to pancreatitis and was found to have a complex, multicystic lesion within the head of the pancreas. He subsequently underwent a pancreatoduodenectomy. Grossly, the mass was 3 cm, multicystic, and well demarcated. Histologically, there were numerous variably sized, dilated ducts lined by tall columnar mucinous cells surrounded by a stroma that exhibited foci of cellular condensations resembling primitive pancreatic mesenchyme. Acinar and endocrine cells were often seen budding into the ducts forming "ductulo-insular bodies." As a result of its superficial resemblance to Stocker type 2 cystic adenomatoid malformation of the lung, we are proposing the name "multicystic adenomatoid hamartoma" for this lesion.

Original languageEnglish (US)
Pages (from-to)314-320
Number of pages7
JournalPediatric and Developmental Pathology
Volume11
Issue number4
DOIs
StatePublished - Jul 1 2008

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

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