Mucinous tubular and spindle cell carcinoma of kidney occurring in a patient with pulmonary adenocarcinoma

Seog Yun Park; Gyeong Hoon Kang; Jae Y. Ro; Jennifer Black; Jinsoo Chung; Kang Hyun Lee; Eun Kyung Hong; Weon Soe Park

Mucinous tubular and spindle cell carcinoma of kidney occurring in a patient with pulmonary adenocarcinoma

Seog Yun Park, Gyeong Hoon Kang, Jae Y. Ro, Jennifer Black, Jinsoo Chung, Kang Hyun Lee, Eun Kyung Hong, Weon Soe Park

Research output: Contribution to journal › Article › peer-review

Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare type of kidney tumor that has only been recently described. Furthermore, a case of MTSCC associated with a simultaneous lung cancer in the same patient has never been reported in the literature. In this paper, we describe a kidney tumor that was detected during staging work-up in a 72-year-old lung cancer patient. The kidney tumor was removed and shown to exhibit histological and immunophenotypic features of MTSCC, completely distinct from the pulmonary adenocarcinoma. In addition, this case was unique because it was characterized by neuroendocrine differentiation as well as p53 and Ki-67 overexpression in tumor cells. Therefore, we report a case of MTSCC diagnosed in a patient with pulmonary adenocarcinoma and describe the detailed histologic and immunohistochemical features of MTSCC.

Original language	English (US)
Pages (from-to)	54-59
Number of pages	6
Journal	Korean Journal of Pathology
Volume	42
Issue number	1
State	Published - 2008

Keywords

Kidney neoplasm
Lung cancer
Multiple primary neoplasm
Spindle cell carcinoma

ASJC Scopus subject areas

Pathology and Forensic Medicine

Cite this

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title = "Mucinous tubular and spindle cell carcinoma of kidney occurring in a patient with pulmonary adenocarcinoma",

abstract = "Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare type of kidney tumor that has only been recently described. Furthermore, a case of MTSCC associated with a simultaneous lung cancer in the same patient has never been reported in the literature. In this paper, we describe a kidney tumor that was detected during staging work-up in a 72-year-old lung cancer patient. The kidney tumor was removed and shown to exhibit histological and immunophenotypic features of MTSCC, completely distinct from the pulmonary adenocarcinoma. In addition, this case was unique because it was characterized by neuroendocrine differentiation as well as p53 and Ki-67 overexpression in tumor cells. Therefore, we report a case of MTSCC diagnosed in a patient with pulmonary adenocarcinoma and describe the detailed histologic and immunohistochemical features of MTSCC.",

keywords = "Kidney neoplasm, Lung cancer, Multiple primary neoplasm, Spindle cell carcinoma",

author = "Park, {Seog Yun} and Kang, {Gyeong Hoon} and Ro, {Jae Y.} and Jennifer Black and Jinsoo Chung and Lee, {Kang Hyun} and Hong, {Eun Kyung} and Park, {Weon Soe}",

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AU - Park, Seog Yun

AU - Kang, Gyeong Hoon

AU - Ro, Jae Y.

AU - Black, Jennifer

AU - Chung, Jinsoo

AU - Lee, Kang Hyun

AU - Hong, Eun Kyung

AU - Park, Weon Soe

PY - 2008

Y1 - 2008

N2 - Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare type of kidney tumor that has only been recently described. Furthermore, a case of MTSCC associated with a simultaneous lung cancer in the same patient has never been reported in the literature. In this paper, we describe a kidney tumor that was detected during staging work-up in a 72-year-old lung cancer patient. The kidney tumor was removed and shown to exhibit histological and immunophenotypic features of MTSCC, completely distinct from the pulmonary adenocarcinoma. In addition, this case was unique because it was characterized by neuroendocrine differentiation as well as p53 and Ki-67 overexpression in tumor cells. Therefore, we report a case of MTSCC diagnosed in a patient with pulmonary adenocarcinoma and describe the detailed histologic and immunohistochemical features of MTSCC.

AB - Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare type of kidney tumor that has only been recently described. Furthermore, a case of MTSCC associated with a simultaneous lung cancer in the same patient has never been reported in the literature. In this paper, we describe a kidney tumor that was detected during staging work-up in a 72-year-old lung cancer patient. The kidney tumor was removed and shown to exhibit histological and immunophenotypic features of MTSCC, completely distinct from the pulmonary adenocarcinoma. In addition, this case was unique because it was characterized by neuroendocrine differentiation as well as p53 and Ki-67 overexpression in tumor cells. Therefore, we report a case of MTSCC diagnosed in a patient with pulmonary adenocarcinoma and describe the detailed histologic and immunohistochemical features of MTSCC.

KW - Kidney neoplasm

KW - Lung cancer

KW - Multiple primary neoplasm

KW - Spindle cell carcinoma

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SN - 1738-1843

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Mucinous tubular and spindle cell carcinoma of kidney occurring in a patient with pulmonary adenocarcinoma

Abstract

Keywords

ASJC Scopus subject areas

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