MR imaging of experimental and clinical thrombi at 1.5 T

James C. Bass, Laurence W. Hedlund, Henry Dirk Sostman

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We have previously reported the T1 and T2 of experimental clots at 0.47 T varies considerably depending upon the method used in their preparation. However, these studies, while relevant to midfield imaging, may not reflect accurately the behavior of such thrombi at higher field strengths. Accordingly, we studied the T1 and T2 at 1.5 T of experimental thrombi prepared by several methods and compared these results with the relaxation times of clinical deep venous thrombi measured in situ in patients. The relationship between the T2 values for the different clot preparation methods was different at 1.5 T than at 0.47 T. The combined use of thrombin and epsilon-amino caproic acid produced thrombi with T1 and T2 indistinguishable from clinical deep venous thrombi.

Original languageEnglish (US)
Pages (from-to)631-635
Number of pages5
JournalMagnetic Resonance Imaging
Volume8
Issue number5
DOIs
StatePublished - Jan 1 1990

Keywords

  • Deep venous thrombosis
  • MRI of experimental thrombi

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Radiology Nuclear Medicine and imaging
  • Structural Biology
  • Clinical Biochemistry
  • Biophysics

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