Morphology of cholesterylester-rich inclusions in lesions of atherosclerosis in man

W. Insull; Y. Hata; J. D. Meakin; L. Marchant; C. W. Andrews; B. Buzek

doi:10.1016/S0021-9150(74)80019-5

Morphology of cholesterylester-rich inclusions in lesions of atherosclerosis in man

W. Insull, Y. Hata, J. D. Meakin, L. Marchant, C. W. Andrews, B. Buzek

Academic Institute

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Cholesteryl ester-rich inclusions, isolated from fatty streak and fibrous plaque lesions and examined by scanning electron microscopy, showed a spherical shape, and frequent lack of substance evidenced by a variety of defects in their surface. The occurrence of these defects may explain some of the inclusions' puzzling pleomorphism observed by transmission electron microscopy.

Original language	English (US)
Pages (from-to)	555-560
Number of pages	6
Journal	Atherosclerosis
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/S0021-9150(74)80019-5
State	Published - 1974

Keywords

Atherosclerosis
Cholesteryl esters
Fatty streaks
Fibrous plaques
Inclusions

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/S0021-9150(74)80019-5

Cite this

@article{833c507e1a1d466086a13e056b65ac72,

title = "Morphology of cholesterylester-rich inclusions in lesions of atherosclerosis in man",

abstract = "Cholesteryl ester-rich inclusions, isolated from fatty streak and fibrous plaque lesions and examined by scanning electron microscopy, showed a spherical shape, and frequent lack of substance evidenced by a variety of defects in their surface. The occurrence of these defects may explain some of the inclusions' puzzling pleomorphism observed by transmission electron microscopy.",

keywords = "Atherosclerosis, Cholesteryl esters, Fatty streaks, Fibrous plaques, Inclusions",

author = "W. Insull and Y. Hata and Meakin, \{J. D.\} and L. Marchant and Andrews, \{C. W.\} and B. Buzek",

note = "Funding Information: Supported by grants from USPHS Nos. HE 5284, HE 6304 and HE 13232, the Zucky Katz Heart Research Foundation, and Ayerst Laboratories. Dr. Insull was an Established Investigator of the American Heart Association during performance of these studies. * Present address: Department of Pathology, College of medicine, Cornell University, and Rockefeller University, New York, N.Y. (U.S.A.) ** Present address: Department of Medicine, School of Medicine, Keio University, Tokyo (Japan). Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1974",

doi = "10.1016/S0021-9150(74)80019-5",

language = "English (US)",

volume = "19",

pages = "555--560",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

TY - JOUR

T1 - Morphology of cholesterylester-rich inclusions in lesions of atherosclerosis in man

AU - Insull, W.

AU - Hata, Y.

AU - Meakin, J. D.

AU - Marchant, L.

AU - Andrews, C. W.

AU - Buzek, B.

N1 - Funding Information: Supported by grants from USPHS Nos. HE 5284, HE 6304 and HE 13232, the Zucky Katz Heart Research Foundation, and Ayerst Laboratories. Dr. Insull was an Established Investigator of the American Heart Association during performance of these studies. * Present address: Department of Pathology, College of medicine, Cornell University, and Rockefeller University, New York, N.Y. (U.S.A.) ** Present address: Department of Medicine, School of Medicine, Keio University, Tokyo (Japan). Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1974

Y1 - 1974

N2 - Cholesteryl ester-rich inclusions, isolated from fatty streak and fibrous plaque lesions and examined by scanning electron microscopy, showed a spherical shape, and frequent lack of substance evidenced by a variety of defects in their surface. The occurrence of these defects may explain some of the inclusions' puzzling pleomorphism observed by transmission electron microscopy.

AB - Cholesteryl ester-rich inclusions, isolated from fatty streak and fibrous plaque lesions and examined by scanning electron microscopy, showed a spherical shape, and frequent lack of substance evidenced by a variety of defects in their surface. The occurrence of these defects may explain some of the inclusions' puzzling pleomorphism observed by transmission electron microscopy.

KW - Atherosclerosis

KW - Cholesteryl esters

KW - Fatty streaks

KW - Fibrous plaques

KW - Inclusions

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U2 - 10.1016/S0021-9150(74)80019-5

DO - 10.1016/S0021-9150(74)80019-5

M3 - Article

C2 - 4828573

AN - SCOPUS:0016364672

SN - 0021-9150

VL - 19

SP - 555

EP - 560

JO - Atherosclerosis

JF - Atherosclerosis

IS - 3

ER -

Morphology of cholesterylester-rich inclusions in lesions of atherosclerosis in man

Abstract

Keywords

ASJC Scopus subject areas

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