Molecular determinants of epothilone B derivative (BMS 247550) and Apo-2L/TRAIL-induced apoptosis of human ovarian cancer cells

Keyphrases

• TRAIL-induced Apoptosis 100%
• Ovarian Cancer Cells 100%
• Epothilone B 100%
• Human Ovarian Cancer Cell 100%
• Molecular Determinants 100%
• Cis-platinum 75%
• Cytotoxic Effect 75%
• Apoptosis 50%
• Immunoblot Analysis 50%
• Survivin 50%
• Paclitaxel-resistant 50%
• Flow Cytometry 25%
• Flow Cytometric 25%
• Induced Apoptosis 25%
• Death Receptor 25%
• Protein Expression 25%
• Cytochrome c (Cyt c) 25%
• Caspase-8 25%
• Caspase 25%
• Caspase-3 25%
• Intracellular Level 25%
• Ovarian Cancer 25%
• Paclitaxel 25%
• Human Ovarian Cancer 25%
• Mitotic Arrest 25%
• Cell Cycle Effects 25%
• MTT Assay 25%
• DIABLO 25%
• Smac 25%
• Caspase-3 Activity 25%
• Tubulin Polymerization 25%
• Proteolytic Activity 25%
• In Vivo Testing 25%
• TUNEL Assay 25%
• Processing Activities 25%
• PARP Cleavage 25%
• Cleavage Activity 25%
• CIAP1 25%
• Annexin V Staining 25%

Medicine and Dentistry

• Cancer Cell 100%
• Programmed Cell Death 100%
• Ovarian Cancer 100%
• Epothilone B 100%
• Cytotoxicity 50%
• Cisplatin 50%
• Paclitaxel 50%
• Cancer 33%
• Cell Cycle 33%
• Immunoblotting 33%
• Caspase 3 33%
• Survivin 33%
• Flow Cytometry 16%
• Protein Expression 16%
• Protein Degradation 16%
• TUNEL Assay 16%
• Caspase 16%
• Cytochrome C 16%
• MTT Assay 16%
• Poly ADP Ribose Polymerase 16%
• Lipocortin 5 16%
• Death Receptor 16%
• Caspase 8 16%
• Microtubule Assembly 16%
• Mitosis Inhibition 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Ovary Cancer 100%
• Epothilone B 100%
• Cytotoxicity 50%
• Cisplatin 50%
• Paclitaxel 50%
• Western Blot 33%
• Caspase 3 33%
• Survivin 33%
• Cytochrome C 16%
• Caspase 8 16%
• Death Receptor 16%
• Caspase 16%
• Flow Cytometry 16%
• Tubulin 16%
• Lipocortin 5 16%