Molecular cloning and characterization of MHC class I- and II-restricted tumor antigens recognized by T cells

Rongfu Wang

doi:10.1002/0471142735.im2010s84

Molecular cloning and characterization of MHC class I- and II-restricted tumor antigens recognized by T cells

Rongfu Wang

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

T cells play a central role in cancer immunosurveillance, autoimmune, and infectious diseases. Identification of MHC class I- and II-restricted T cell peptides is a critical step for the development of effective vaccines against cancer and infectious diseases. This unit describes a cDNA expression system and a genetic targeting expression system for the cloning of genes encoding forMHC class I- and II-restricted antigens recognized by antigen-specific CD8⁺ and CD4⁺ T cells.

Original language	English (US)
Journal	Current Protocols in Immunology
Issue number	SUPPL. 84
DOIs	https://doi.org/10.1002/0471142735.im2010s84
State	Published - Mar 12 2009

Keywords

Cancer vaccines
CD4 T cells
cDNA library
Immunotherapy
MHC class II
T helper peptides
Targeting expression
Tumor antigens

ASJC Scopus subject areas

Immunology

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10.1002/0471142735.im2010s84

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title = "Molecular cloning and characterization of MHC class I- and II-restricted tumor antigens recognized by T cells",

abstract = "T cells play a central role in cancer immunosurveillance, autoimmune, and infectious diseases. Identification of MHC class I- and II-restricted T cell peptides is a critical step for the development of effective vaccines against cancer and infectious diseases. This unit describes a cDNA expression system and a genetic targeting expression system for the cloning of genes encoding forMHC class I- and II-restricted antigens recognized by antigen-specific CD8+ and CD4+ T cells.",

keywords = "Cancer vaccines, CD4 T cells, cDNA library, Immunotherapy, MHC class II, T helper peptides, Targeting expression, Tumor antigens",

author = "Rongfu Wang",

year = "2009",

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doi = "10.1002/0471142735.im2010s84",

language = "English (US)",

journal = "Current Protocols in Immunology",

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PY - 2009/3/12

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AB - T cells play a central role in cancer immunosurveillance, autoimmune, and infectious diseases. Identification of MHC class I- and II-restricted T cell peptides is a critical step for the development of effective vaccines against cancer and infectious diseases. This unit describes a cDNA expression system and a genetic targeting expression system for the cloning of genes encoding forMHC class I- and II-restricted antigens recognized by antigen-specific CD8+ and CD4+ T cells.

KW - Cancer vaccines

KW - CD4 T cells

KW - cDNA library

KW - Immunotherapy

KW - MHC class II

KW - T helper peptides

KW - Targeting expression

KW - Tumor antigens

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U2 - 10.1002/0471142735.im2010s84

DO - 10.1002/0471142735.im2010s84

M3 - Review article

C2 - 19235768

AN - SCOPUS:61749095015

SN - 1934-3671

JO - Current Protocols in Immunology

JF - Current Protocols in Immunology

IS - SUPPL. 84

ER -

Molecular cloning and characterization of MHC class I- and II-restricted tumor antigens recognized by T cells

Abstract

Keywords

ASJC Scopus subject areas

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