Abstract
The Cancer Genome Atlas (TCGA) uveal melanoma project was a comprehensive multi-platform deep molecular investigation of 80 uveal melanoma primary tissue samples supported by the National Cancer Institute. In addition to identification of important mutations for the first time, it identified four different clusters (subgroups) of patients paralleling prognosis. The findings of the TCGA marker paper are summarized in this review manuscript and other investigations that have stemmed from the findings of the TCGA project are reviewed.
| Original language | English (US) |
|---|---|
| Article number | 1061 |
| Journal | Cancers |
| Volume | 11 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2019 |
Keywords
- Immune infiltrates
- Methylation
- RNA seq
- TCGA
- Uveal melanoma
- Whole exome sequencing
ASJC Scopus subject areas
- Oncology
- Cancer Research
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