Molecular alterations and lung tumors in p53 mutant mice exposed to cigarette smoke

Medicine & Life Sciences

• Smoke 100%
• Tobacco Products 98%
• Lung 55%
• Neoplasms 33%
• DNA Adducts 32%
• Alveolar Macrophages 19%
• Environmental Exposure 18%
• Heart 16%
• Mutation 14%
• Lung Neoplasms 13%
• Erythrocytes 13%
• 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 13%
• Li-Fraumeni Syndrome 13%
• Carcinogenesis 13%
• Epithelium 13%
• Tumor Suppressor Protein p53 11%
• Benzo(a)pyrene 10%
• Sequence Deletion 9%
• Complex Mixtures 9%
• Transgenes 8%
• Germ Cells 8%
• Cytogenetics 8%
• Incidence 8%
• Carcinogens 8%
• Weight Gain 7%
• Transgenic Mice 7%
• DNA Damage 7%
• Smokers 7%
• Air 6%
• Epidemiology 6%
• Alleles 6%
• Animal Models 6%
• Body Weight 6%
• Genome 5%
• Cell Proliferation 5%
• Apoptosis 5%