Modulation of DNA‐binding specificity within the nuclear receptor family by substitutions at a single amino acid position

Medicine & Life Sciences

• Nuclear Family 100%
• Cytoplasmic and Nuclear Receptors 95%
• Amino Acids 65%
• DNA 51%
• Transcription Factors 41%
• Response Elements 40%
• Hydrogen Bonding 22%
• Glucocorticoid Receptors 20%
• Amino Acid Substitution 20%
• Gene Expression Regulation 20%
• Mutant Proteins 19%
• Base Pairing 19%
• Glycine 18%
• Estrogen Receptors 17%
• Glutamic Acid 16%
• Data Analysis 13%
• Mutation 10%
• Proteins 6%

Chemistry

• Glucocorticoid 59%
• Substitution Reaction 58%
• Estrogen 49%
• Molecular Modeling 42%
• Mutation 39%
• Protein 38%
• Acid 32%
• Hydrogen Bond 28%