We demonstrate that silicon AFM tips can be modified by etching with 2% HF solution followed by reaction with an α,ω-oligo(ethylene glycol)alkene. Tips properly modified by this technique maintain a small tip size and effectively reduce the nonspecific interaction with fibrinogen and bovine serum albumin, resulting in greatly improved image resolution and contrast for high-coverage fibrinogen films.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of the American Chemical Society|
|State||Published - Jun 25 2003|
ASJC Scopus subject areas
- Colloid and Surface Chemistry