Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data

A. Belfatto; M. Garbey; M. Riboldi; D. Ciardo; A. Cecconi; R. Lazzari; B. A. Jereczek; R. Orecchia; G. Baroni; P. Cerveri

doi:10.1109/BHI.2014.6864406

Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data

A. Belfatto, M. Garbey, M. Riboldi, D. Ciardo, A. Cecconi, R. Lazzari, B. A. Jereczek, R. Orecchia, G. Baroni, P. Cerveri

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Mathematical modeling of the tumor response to radiotherapy may provide a meaningful contribution to enhance the therapeutic planning and adjust the treatment on the run. Clinical translation of modeling results is currently prevented by the lack of sufficient validation on a patient-specific basis while imaging techniques along with the latest treatments (e.g. IGRT) can make available a large number of patient data at macroscopic scale. In this work, tissue-scale tumor growth and radio-response models are proposed and validated on volume regression data measured on serial CBCT imaging, concurrent with the treatment fractions, of 16 cervix cancer patients.

Original language	English (US)
Title of host publication	2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	476-479
Number of pages	4
ISBN (Print)	9781479921317
DOIs	https://doi.org/10.1109/BHI.2014.6864406
State	Published - Jan 1 2014
Event	2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014 - Valencia, Spain Duration: Jun 1 2014 → Jun 4 2014

Other

Other	2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014
Country/Territory	Spain
City	Valencia
Period	6/1/14 → 6/4/14

ASJC Scopus subject areas

Biomedical Engineering
Health Informatics

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10.1109/BHI.2014.6864406

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Belfatto, A., Garbey, M., Riboldi, M., Ciardo, D., Cecconi, A., Lazzari, R., Jereczek, B. A., Orecchia, R., Baroni, G., & Cerveri, P. (2014). Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data. In 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014 (pp. 476-479). Article 6864406 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BHI.2014.6864406

Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data. / Belfatto, A.; Garbey, M.; Riboldi, M. et al.
2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 476-479 6864406.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Belfatto, A, Garbey, M, Riboldi, M, Ciardo, D, Cecconi, A, Lazzari, R, Jereczek, BA, Orecchia, R, Baroni, G & Cerveri, P 2014, Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data. in 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014., 6864406, Institute of Electrical and Electronics Engineers Inc., pp. 476-479, 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014, Valencia, Spain, 6/1/14. https://doi.org/10.1109/BHI.2014.6864406

Belfatto A, Garbey M, Riboldi M, Ciardo D, Cecconi A, Lazzari R et al. Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data. In 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 476-479. 6864406 doi: 10.1109/BHI.2014.6864406

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Modeling cervix cancer growth and response to radiation therapy: A validation study using patient volumetric tumor data

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