Mixed neuronal-glial tumors (gangliogliomas) in children

Murali Chintagumpala; Dawna Armstrong; Seiko Miki; Tess Nelson; William Cheek; John Laurent; Shiao Y. Woo; Donald H. Mahoney

doi:10.1159/000121060

Mixed neuronal-glial tumors (gangliogliomas) in children

Murali Chintagumpala, Dawna Armstrong, Seiko Miki, Tess Nelson, William Cheek, John Laurent, Shiao Y. Woo, Donald H. Mahoney

Houston Methodist

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Mixed tumors account for about 10% of the childhood central nervous system tumors. Studies of the most common tumor, the ganglioglioma, in patients of all ages suggest that optimal therapy is total gross resection. There are few studies on these tumors in children. In our institution between 1984 and 1993, 28 children with gangliogliomas (4 of which were anaplastic) and 4 children with dysembryoplastic neuroepithelial tumors were treated and followed. Fourteen had local subarachnoid involvement. Total gross resection was usually curative, regardless of histology. Subarachnoid involvement was not indicative of a poorer prognosis.

Original language	English (US)
Pages (from-to)	306-313
Number of pages	8
Journal	Pediatric Neurosurgery
Volume	24
Issue number	6
DOIs	https://doi.org/10.1159/000121060
State	Published - Jan 1 1996

Keywords

Anaplasia
Ganglioglioma
Mixed neuronal-glial tumors
Neuroepithelial neoplasms
Neuroglia
Seizures
Subarachnoid involvement

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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10.1159/000121060

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abstract = "Mixed tumors account for about 10% of the childhood central nervous system tumors. Studies of the most common tumor, the ganglioglioma, in patients of all ages suggest that optimal therapy is total gross resection. There are few studies on these tumors in children. In our institution between 1984 and 1993, 28 children with gangliogliomas (4 of which were anaplastic) and 4 children with dysembryoplastic neuroepithelial tumors were treated and followed. Fourteen had local subarachnoid involvement. Total gross resection was usually curative, regardless of histology. Subarachnoid involvement was not indicative of a poorer prognosis.",

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AU - Chintagumpala, Murali

AU - Armstrong, Dawna

AU - Miki, Seiko

AU - Nelson, Tess

AU - Cheek, William

AU - Laurent, John

AU - Woo, Shiao Y.

AU - Mahoney, Donald H.

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AB - Mixed tumors account for about 10% of the childhood central nervous system tumors. Studies of the most common tumor, the ganglioglioma, in patients of all ages suggest that optimal therapy is total gross resection. There are few studies on these tumors in children. In our institution between 1984 and 1993, 28 children with gangliogliomas (4 of which were anaplastic) and 4 children with dysembryoplastic neuroepithelial tumors were treated and followed. Fourteen had local subarachnoid involvement. Total gross resection was usually curative, regardless of histology. Subarachnoid involvement was not indicative of a poorer prognosis.

KW - Anaplasia

KW - Ganglioglioma

KW - Mixed neuronal-glial tumors

KW - Neuroepithelial neoplasms

KW - Neuroglia

KW - Seizures

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Mixed neuronal-glial tumors (gangliogliomas) in children

Abstract

Keywords

ASJC Scopus subject areas

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