Mixed neuronal-glial tumors (gangliogliomas) in children

Murali Chintagumpala, Dawna Armstrong, Seiko Miki, Tess Nelson, William Cheek, John Laurent, Shiao Y. Woo, Donald H. Mahoney

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Mixed tumors account for about 10% of the childhood central nervous system tumors. Studies of the most common tumor, the ganglioglioma, in patients of all ages suggest that optimal therapy is total gross resection. There are few studies on these tumors in children. In our institution between 1984 and 1993, 28 children with gangliogliomas (4 of which were anaplastic) and 4 children with dysembryoplastic neuroepithelial tumors were treated and followed. Fourteen had local subarachnoid involvement. Total gross resection was usually curative, regardless of histology. Subarachnoid involvement was not indicative of a poorer prognosis.

Original languageEnglish (US)
Pages (from-to)306-313
Number of pages8
JournalPediatric Neurosurgery
Volume24
Issue number6
DOIs
StatePublished - Jan 1 1996

Keywords

  • Anaplasia
  • Ganglioglioma
  • Mixed neuronal-glial tumors
  • Neuroepithelial neoplasms
  • Neuroglia
  • Seizures
  • Subarachnoid involvement

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Mixed neuronal-glial tumors (gangliogliomas) in children'. Together they form a unique fingerprint.

Cite this