Mixed neuronal-glial tumors (gangliogliomas) in children

Murali Chintagumpala, Dawna Armstrong, Seiko Miki, Tess Nelson, William Cheek, John Laurent, Shiao Y. Woo, Donald H. Mahoney

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Mixed tumors account for about 10% of the childhood central nervous system tumors. Studies of the most common tumor, the ganglioglioma, in patients of all ages suggest that optimal therapy is total gross resection. There are few studies on these tumors in children. In our institution between 1984 and 1993, 28 children with gangliogliomas (4 of which were anaplastic) and 4 children with dysembryoplastic neuroepithelial tumors were treated and followed. Fourteen had local subarachnoid involvement. Total gross resection was usually curative, regardless of histology. Subarachnoid involvement was not indicative of a poorer prognosis.

Original languageEnglish (US)
Pages (from-to)306-313
Number of pages8
JournalPediatric Neurosurgery
Issue number6
StatePublished - Jan 1 1996


  • Anaplasia
  • Ganglioglioma
  • Mixed neuronal-glial tumors
  • Neuroepithelial neoplasms
  • Neuroglia
  • Seizures
  • Subarachnoid involvement

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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