Misdiagnosis of Silent Sinus Syndrome

John R. Burroughs, Jorge R. Hernández Cospín, Charles N. Soparkar, James R. Patrinely

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations


Purpose: To review cases of spontaneous enophthalmos erroneously diagnosed as silent sinus syndrome to identify other inflammatory disorders with a similar clinical presentation. Methods: Retrospective observational case series. Chart reviews were performed covering encounters over a 5-year period, searching for patients referred to two physicians with an incorrect diagnosis of silent sinus syndrome. Only cases of acquired enophthalmos of reported nontraumatic or nonneoplastic cause were included. Particular attention was directed toward noting clinical features of upper eyelid position and periocular atrophy. Results: Nineteen cases of erroneous referral for silent sinus syndrome were identified. Fourteen of these cases were due to tumor, trauma, congenital facial asymmetry, or diffuse facial lipodystrophy. Among the remaining cases, four were diagnosed as Parry-Romberg syndrome and one as linear scleroderma. Conclusions: Parry-Romberg syndrome and linear scleroderma must be distinguished from silent sinus syndrome as causes of inflammatory-mediated, spontaneous enophthalmos.

Original languageEnglish (US)
Pages (from-to)449-454
Number of pages6
JournalOphthalmic Plastic and Reconstructive Surgery
Issue number6
StatePublished - Nov 1 2003

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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