TY - JOUR
T1 - MiRNAs in colon and rectal cancer
T2 - A consensus for their true clinical value
AU - Agostini, Marco
AU - Pucciarelli, Salvatore
AU - Calore, Federica
AU - Bedin, Chiara
AU - Enzo, Maria Vittoria
AU - Nitti, Donato
PY - 2010/9
Y1 - 2010/9
N2 - Numerous miRNAs are deregulated in human cancers and experimental evidence indicates that they can play roles as oncogenes or tumor suppressor genes.Colorectal cancer represents a wide and exciting area of research for molecular biology, due to the growing need of a molecular classification as well as prognostic and predictive molecular factors that may guide oncologists in the clinical management of patients. The aim of this review is to analyze the state of art of the miRNA expression profiles in colorectal cancer to explore some perspectives in this research field.
AB - Numerous miRNAs are deregulated in human cancers and experimental evidence indicates that they can play roles as oncogenes or tumor suppressor genes.Colorectal cancer represents a wide and exciting area of research for molecular biology, due to the growing need of a molecular classification as well as prognostic and predictive molecular factors that may guide oncologists in the clinical management of patients. The aim of this review is to analyze the state of art of the miRNA expression profiles in colorectal cancer to explore some perspectives in this research field.
KW - Colorectal cancer
KW - MicroRNAs
UR - http://www.scopus.com/inward/record.url?scp=77954216489&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954216489&partnerID=8YFLogxK
U2 - 10.1016/j.cca.2010.05.002
DO - 10.1016/j.cca.2010.05.002
M3 - Review article
C2 - 20452339
AN - SCOPUS:77954216489
SN - 0009-8981
VL - 411
SP - 1181
EP - 1186
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
IS - 17-18
ER -