MiRNAs in colon and rectal cancer: A consensus for their true clinical value

Marco Agostini, Salvatore Pucciarelli, Federica Calore, Chiara Bedin, Maria Vittoria Enzo, Donato Nitti

Research output: Contribution to journalReview article

35 Scopus citations

Abstract

Numerous miRNAs are deregulated in human cancers and experimental evidence indicates that they can play roles as oncogenes or tumor suppressor genes.Colorectal cancer represents a wide and exciting area of research for molecular biology, due to the growing need of a molecular classification as well as prognostic and predictive molecular factors that may guide oncologists in the clinical management of patients. The aim of this review is to analyze the state of art of the miRNA expression profiles in colorectal cancer to explore some perspectives in this research field.

Original languageEnglish (US)
Pages (from-to)1181-1186
Number of pages6
JournalClinica Chimica Acta
Volume411
Issue number17-18
DOIs
StatePublished - Sep 1 2010

Keywords

  • Colorectal cancer
  • MicroRNAs

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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