Midterm Outcomes of the Self-Expanding Navitor Transcatheter Heart Valve: A Systematic Review and Meta-Analysis

Sahar Samimi; Chloe Kharsa; Mangesh Kritya; Joe Aoun; Syed Zaid; Nadeen N. Faza; Stephen H. Little; Neal S. Kleiman; Michael J. Reardon; Sachin S. Goel

doi:10.1016/j.shj.2025.100750

Midterm Outcomes of the Self-Expanding Navitor Transcatheter Heart Valve: A Systematic Review and Meta-Analysis

Sahar Samimi, Chloe Kharsa, Mangesh Kritya, Joe Aoun, Syed Zaid, Nadeen N. Faza, Stephen H. Little, Neal S. Kleiman, Michael J. Reardon, Sachin S. Goel

Research output: Contribution to journal › Article › peer-review

Abstract

•A 19-study meta-analysis (7743 patients) found high Navitor technical/device success.•≥Moderate PVL was low: 1.3% at 30 days and 0.6% at 1 year.•Pacemaker implantation was 16.7% at 30 days and 20.4% at 1 year.•Thirty-day outcomes were favorable: all-cause mortality 1.5% and stroke 1.7%.

Original language	English (US)
Article number	100750
Pages (from-to)	100750
Journal	Structural Heart
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/j.shj.2025.100750
State	Published - Jan 2026

Keywords

Meta-analysis
Navitor
TAVI
TAVR
Transcatheter aortic valve implantation
Transcatheter aortic valve replacement

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.shj.2025.100750

Cite this

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title = "Midterm Outcomes of the Self-Expanding Navitor Transcatheter Heart Valve: A Systematic Review and Meta-Analysis",

abstract = "•A 19-study meta-analysis (7743 patients) found high Navitor technical/device success.•≥Moderate PVL was low: 1.3\% at 30 days and 0.6\% at 1 year.•Pacemaker implantation was 16.7\% at 30 days and 20.4\% at 1 year.•Thirty-day outcomes were favorable: all-cause mortality 1.5\% and stroke 1.7\%.",

keywords = "Meta-analysis, Navitor, TAVI, TAVR, Transcatheter aortic valve implantation, Transcatheter aortic valve replacement",

author = "Sahar Samimi and Chloe Kharsa and Mangesh Kritya and Joe Aoun and Syed Zaid and Faza, \{Nadeen N.\} and Little, \{Stephen H.\} and Kleiman, \{Neal S.\} and Reardon, \{Michael J.\} and Goel, \{Sachin S.\}",

note = "{\textcopyright} 2025 The Author(s).",

year = "2026",

month = jan,

doi = "10.1016/j.shj.2025.100750",

language = "English (US)",

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TY - JOUR

T1 - Midterm Outcomes of the Self-Expanding Navitor Transcatheter Heart Valve

T2 - A Systematic Review and Meta-Analysis

AU - Samimi, Sahar

AU - Kharsa, Chloe

AU - Kritya, Mangesh

AU - Aoun, Joe

AU - Zaid, Syed

AU - Faza, Nadeen N.

AU - Little, Stephen H.

AU - Kleiman, Neal S.

AU - Reardon, Michael J.

AU - Goel, Sachin S.

PY - 2026/1

Y1 - 2026/1

N2 - •A 19-study meta-analysis (7743 patients) found high Navitor technical/device success.•≥Moderate PVL was low: 1.3% at 30 days and 0.6% at 1 year.•Pacemaker implantation was 16.7% at 30 days and 20.4% at 1 year.•Thirty-day outcomes were favorable: all-cause mortality 1.5% and stroke 1.7%.

AB - •A 19-study meta-analysis (7743 patients) found high Navitor technical/device success.•≥Moderate PVL was low: 1.3% at 30 days and 0.6% at 1 year.•Pacemaker implantation was 16.7% at 30 days and 20.4% at 1 year.•Thirty-day outcomes were favorable: all-cause mortality 1.5% and stroke 1.7%.

KW - Meta-analysis

KW - Navitor

KW - TAVI

KW - TAVR

KW - Transcatheter aortic valve implantation

KW - Transcatheter aortic valve replacement

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ER -

Midterm Outcomes of the Self-Expanding Navitor Transcatheter Heart Valve: A Systematic Review and Meta-Analysis

Abstract

Keywords

ASJC Scopus subject areas

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