TY - JOUR
T1 - Mid-cavity obstruction in apical hypertrophy
T2 - Doppler evidence of diastolic intraventricular gradient with higher apical pressure
AU - Zoghbi, William A.
AU - Haichin, Richard N.
AU - Quiñones, Miguel A.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Three cases of apical left ventricular hypertrophy demonstrating a sequestered small left ventricular apical cavity with complete systolic and partial diastolic intraventricular obstruction are described. Doppler studies revealed that flow from the apical chamber is aborted during early systole with further emptying during diastole through a narrow intraventricular channel, where a diastolic high-velocity jet (≥2.5 m/sec) directed from apex to base was localized. This indicated a significantly higher pressure in early diastole in the sequestered apical cavity. Filling of the apical chamber occurred late in diastole and during isovolumic ventricular contraction. The observations by Doppler of complete intraventricular systolic and partial diastolic obstruction in apical hypertrophy are new and may have significant clinical implications.
AB - Three cases of apical left ventricular hypertrophy demonstrating a sequestered small left ventricular apical cavity with complete systolic and partial diastolic intraventricular obstruction are described. Doppler studies revealed that flow from the apical chamber is aborted during early systole with further emptying during diastole through a narrow intraventricular channel, where a diastolic high-velocity jet (≥2.5 m/sec) directed from apex to base was localized. This indicated a significantly higher pressure in early diastole in the sequestered apical cavity. Filling of the apical chamber occurred late in diastole and during isovolumic ventricular contraction. The observations by Doppler of complete intraventricular systolic and partial diastolic obstruction in apical hypertrophy are new and may have significant clinical implications.
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U2 - 10.1016/0002-8703(88)90730-2
DO - 10.1016/0002-8703(88)90730-2
M3 - Article
C2 - 3195430
AN - SCOPUS:0024206649
SN - 0002-8703
VL - 116
SP - 1469
EP - 1474
JO - American Heart Journal
JF - American Heart Journal
IS - 6 PART 1
ER -