Abstract
Deformability is a critical parameter for discriminating healthy and diseased cells [1]. Several complex microfluidics devices are currently available for separating cells with different deformabilities. Viscoelastic fluids have also been used for particle/cell separation to simplify the microfluidic design [2]. Channel design strongly depends on both fluid rheology [3] and cell deformability [4]. In this work, we study the effect of cell deformability on particle/cell migration perpendicular to the flow, using particles/cells with similar sizes, but different deformabilities, suspended in 2 different viscoelastic fluids, in a straight 150 μm square-shaped microchannel.
| Original language | English (US) |
|---|---|
| Title of host publication | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 838-839 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780979806490 |
| State | Published - 2016 |
| Event | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: Oct 9 2016 → Oct 13 2016 |
Other
| Other | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| Country/Territory | Ireland |
| City | Dublin |
| Period | 10/9/16 → 10/13/16 |
Keywords
- Cell migration
- Deformability
- Focusing
- Viscoelastic
ASJC Scopus subject areas
- Control and Systems Engineering