Abstract
The application of microfabrication technology to create precise separation and isolation membranes for biomedical applications is reviewed. By utilizing standard microfabrication techniques, membranes were fabricated with well-controlled and uniform pore sizes, allowing the optimization of membrane parameters for cell immunoisolation. The membrane forming process employs bulk and surface micromachining to define chambers within single crystalline silicon wafers that interface with the surrounding biological environment through polycrystalline silicon filter membranes. Membranes were fabricated to present a high density of uniform pores to allow sufficient permeability to nutrients while preventing the passage of immunoglobulin G. The semipermeability of microfabricated membranes, their biocompatibility, ease in sterilization, along with their thermal and chemical stability, may provide significant advantages for biomedical applications.
| Original language | English (US) |
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| Title of host publication | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| Number of pages | 1 |
| Volume | 2 |
| ISBN (Print) | 0780356756 |
| State | Published - Dec 1 1999 |
| Event | Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA Duration: Oct 13 1999 → Oct 16 1999 |
Other
| Other | Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) |
|---|---|
| City | Atlanta, GA, USA |
| Period | 10/13/99 → 10/16/99 |
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics