Microbial demethylation and debutynylation of four phenylurea herbicides

P. R. Wallnöfer, S. Safe, O. Hutzinger

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Rhizopus japonicus demethylates the herbicides monuron, fluometuron, and monolinuron into the metabolites 3-(p-chlorophenyl)-1-methylurea (V), 3-(m-trifluormethylphenyl)-1-methylurea (VI), and 3-(p-chlorophenyl)-1-methoxyurea (VII), respectively. Buturon loses its N-(1-methyl-2-propynyl) group to give compound V. These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis accumulate after a 1-wk growth.

Original languageEnglish (US)
Pages (from-to)253-258
Number of pages6
JournalPesticide Biochemistry and Physiology
Issue number3
StatePublished - Sep 1973

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Health, Toxicology and Mutagenesis


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