Abstract
Microorganisms express a family of cell-surface adhesins that specifically recognize and bind components of the extracellular matrix. Adhesion of microorganisms to host tissues represents a critical phase in the development of many types of infections. Recent studies have focused on the mechanisms of microbial attachment at a molecular level, including the identification of ligand-binding domains in several cell-surface adhesins from Gram-positive bacteria and the construction of adhesin-deficient isogenic mutants.
Original language | English (US) |
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Pages (from-to) | 752-758 |
Number of pages | 7 |
Journal | Current Opinion in Cell Biology |
Volume | 6 |
Issue number | 5 |
DOIs | |
State | Published - Oct 1994 |
ASJC Scopus subject areas
- Cell Biology