Metastatic uterine papillary serous carcinoma to the pericardium

Pedro T. Ramirez, Lois M. Ramondetta, Thomas W. Burke, David M. Gershenson, Molly A. Brewer

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background. Uterine papillary serous carcinoma is an aggressive tumor with a high propensity for distant spread. Metastases to the heart or pericardium are rare in gynecologic malignancies and usually fatal. Case. A 64-year-old African American woman was diagnosed with recurrent uterine papillary serous carcinoma metastatic to the pericardium. Her case at presentation was significant for an elevated serum CA-125, evidence of metastatic disease to the liver, and massive cardiomegaly. Cytologic analysis of fluid obtained by pericardiocentesis confirmed recurrence. Despite treatment with paclitaxel and a pleuropericardial window, the patient succumbed to her disease. Conclusion. The prognosis for patients whose recurrent uterine papillary serous carcinoma has metastasized to the heart or pericardium is extremely poor. Effective adjuvant and salvage therapies are essential.

Original languageEnglish (US)
Pages (from-to)135-137
Number of pages3
JournalGynecologic oncology
Issue number1
StatePublished - 2001


  • Papillary serous adenocarcinoma
  • Pericardial metastasis
  • Uterine cancer

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology


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