Metastatic adult granulosa cell tumor mimicking a benign pancreatic cyst

Rania A. Abadeer, Jason B. Fleming, Michael T. Deavers, Asif Rashid, Douglas B. Evans, Huamin Wang

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We report an unusual case of metastatic adult granulosa cell tumor in the head of pancreas mimicking a benign pancreatic cyst in a 43-year-old female. Clinically, it was considered a benign cyst of the pancreas based on its appearance by imaging and that repeated fine-needle aspiration and cytologic examination of cystic fluid failed to identify malignant cells. The cyst in her pancreas grew slowly during the 15 months of close follow-up. Subsequent drainage and open biopsy of the cyst wall established the diagnosis of metastatic adult granulosa cell tumor that was confirmed in pancreaticoduodenectomy specimen. Immunohistochemical study and clinical history were critical to make the correct diagnosis and to differentiate this tumor from other more commonly encountered cystic neoplasms of the pancreas.

Original languageEnglish (US)
Pages (from-to)457-460
Number of pages4
JournalAnnals of Diagnostic Pathology
Volume14
Issue number6
DOIs
StatePublished - Dec 2010

Keywords

  • Adult granulosa cell tumor
  • Cystic neoplasm of the pancreas
  • Pancreas
  • Pancreatic cyst

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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