Metabolism of the systemic fungicides 2-methylbenzanilide and 2-chlorobenzanilide by Rhizopus japonicus

P. R. Wallnöfer; S. Safe; O. Hutzinger

doi:10.1016/0048-3575(71)90179-9

Metabolism of the systemic fungicides 2-methylbenzanilide and 2-chlorobenzanilide by Rhizopus japonicus

P. R. Wallnöfer, S. Safe, O. Hutzinger

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Rhizopus japonicus convert the systemic fungicides 2-methylbenzanilide (BAS-305) and 2-chlorobenzanilide (BAS-307) into the corresponding p-hydroxyanilino derivatives (i.e., 2-methyl-4′-hydroxybenzanilide and 2-chloro-4′-hydroxybenzanilide). The structures of the metabolites were elucidated by nuclear magnetic resonance and mass spectrometric analysis and confirmed by synthesis. Metabolites appeared with the beginning of the exponential growth-phase and highest concentrations were reached when fungal growth ended.

Original language	English (US)
Pages (from-to)	458-463
Number of pages	6
Journal	Pesticide Biochemistry and Physiology
Volume	1
Issue number	3-4
DOIs	https://doi.org/10.1016/0048-3575(71)90179-9
State	Published - Dec 1971

ASJC Scopus subject areas

Agronomy and Crop Science
Health, Toxicology and Mutagenesis

Access to Document

10.1016/0048-3575(71)90179-9

Cite this

@article{99465e8ef6be4bba80bbf557c22321c3,

title = "Metabolism of the systemic fungicides 2-methylbenzanilide and 2-chlorobenzanilide by Rhizopus japonicus",

abstract = "Rhizopus japonicus convert the systemic fungicides 2-methylbenzanilide (BAS-305) and 2-chlorobenzanilide (BAS-307) into the corresponding p-hydroxyanilino derivatives (i.e., 2-methyl-4′-hydroxybenzanilide and 2-chloro-4′-hydroxybenzanilide). The structures of the metabolites were elucidated by nuclear magnetic resonance and mass spectrometric analysis and confirmed by synthesis. Metabolites appeared with the beginning of the exponential growth-phase and highest concentrations were reached when fungal growth ended.",

author = "Walln{\"o}fer, {P. R.} and S. Safe and O. Hutzinger",

year = "1971",

month = dec,

doi = "10.1016/0048-3575(71)90179-9",

language = "English (US)",

volume = "1",

pages = "458--463",

journal = "Pesticide Biochemistry and Physiology",

issn = "0048-3575",

publisher = "Academic Press",

number = "3-4",

}

TY - JOUR

T1 - Metabolism of the systemic fungicides 2-methylbenzanilide and 2-chlorobenzanilide by Rhizopus japonicus

AU - Wallnöfer, P. R.

AU - Safe, S.

AU - Hutzinger, O.

PY - 1971/12

Y1 - 1971/12

N2 - Rhizopus japonicus convert the systemic fungicides 2-methylbenzanilide (BAS-305) and 2-chlorobenzanilide (BAS-307) into the corresponding p-hydroxyanilino derivatives (i.e., 2-methyl-4′-hydroxybenzanilide and 2-chloro-4′-hydroxybenzanilide). The structures of the metabolites were elucidated by nuclear magnetic resonance and mass spectrometric analysis and confirmed by synthesis. Metabolites appeared with the beginning of the exponential growth-phase and highest concentrations were reached when fungal growth ended.

AB - Rhizopus japonicus convert the systemic fungicides 2-methylbenzanilide (BAS-305) and 2-chlorobenzanilide (BAS-307) into the corresponding p-hydroxyanilino derivatives (i.e., 2-methyl-4′-hydroxybenzanilide and 2-chloro-4′-hydroxybenzanilide). The structures of the metabolites were elucidated by nuclear magnetic resonance and mass spectrometric analysis and confirmed by synthesis. Metabolites appeared with the beginning of the exponential growth-phase and highest concentrations were reached when fungal growth ended.

UR - http://www.scopus.com/inward/record.url?scp=25544449369&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=25544449369&partnerID=8YFLogxK

U2 - 10.1016/0048-3575(71)90179-9

DO - 10.1016/0048-3575(71)90179-9

M3 - Article

AN - SCOPUS:25544449369

SN - 0048-3575

VL - 1

SP - 458

EP - 463

JO - Pesticide Biochemistry and Physiology

JF - Pesticide Biochemistry and Physiology

IS - 3-4

ER -

Metabolism of the systemic fungicides 2-methylbenzanilide and 2-chlorobenzanilide by Rhizopus japonicus

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this