Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

Peter R. Wallnöfer; Manfred Königer; Steve Safe; Otto Hutzinger; Steve Safe; Otto Hutzinger

doi:10.1021/jf60179a027

Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

Peter R. Wallnöfer, Manfred Königer, Steve Safe, Otto Hutzinger, Steve Safe, Otto Hutzinger

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.

Original language	English (US)
Pages (from-to)	20-22
Number of pages	3
Journal	Journal of Agricultural and Food Chemistry
Volume	20
Issue number	1
DOIs	https://doi.org/10.1021/jf60179a027
State	Published - Jan 1 1972

ASJC Scopus subject areas

General Chemistry
General Agricultural and Biological Sciences

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abstract = "Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.",

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AU - Wallnöfer, Peter R.

AU - Königer, Manfred

AU - Safe, Steve

AU - Hutzinger, Otto

AU - Safe, Steve

AU - Hutzinger, Otto

PY - 1972/1/1

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AB - Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.

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Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

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