Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

Peter R. Wallnöfer; Manfred Königer; Steve Safe; Otto Hutzinger; Steve Safe; Otto Hutzinger

doi:10.1021/jf60179a027

Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

Peter R. Wallnöfer, Manfred Königer, Steve Safe, Otto Hutzinger, Steve Safe, Otto Hutzinger

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.

Original language	English (US)
Pages (from-to)	20-22
Number of pages	3
Journal	Journal of Agricultural and Food Chemistry
Volume	20
Issue number	1
DOIs	https://doi.org/10.1021/jf60179a027
State	Published - Jan 1 1972

ASJC Scopus subject areas

Chemistry(all)
Agricultural and Biological Sciences(all)

Access to Document

10.1021/jf60179a027

Cite this

@article{39eba4ce149b4d69b6c61b5008b9175c,

title = "Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi",

abstract = "Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.",

author = "Walln{\"o}fer, {Peter R.} and Manfred K{\"o}niger and Steve Safe and Otto Hutzinger and Steve Safe and Otto Hutzinger",

year = "1972",

month = jan,

day = "1",

doi = "10.1021/jf60179a027",

language = "English (US)",

volume = "20",

pages = "20--22",

journal = "Journal of Agricultural and Food Chemistry",

issn = "0021-8561",

publisher = "American Chemical Society",

number = "1",

}

TY - JOUR

T1 - Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

AU - Wallnöfer, Peter R.

AU - Königer, Manfred

AU - Safe, Steve

AU - Hutzinger, Otto

AU - Safe, Steve

AU - Hutzinger, Otto

PY - 1972/1/1

Y1 - 1972/1/1

N2 - Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.

AB - Rhizopus japonicus and related fungi convert the systemic fungicide 2,3-dimethyl-3-furancarboxylic acid anilide (BAS 3191) into two metabolites, 2-hydroxymethyl-5-methyl-3-furancarboxylic acid anilide (M-2) and 2-methyl-5-hydroxymethyl-3-furan-carboxylic acid anilide (M-l). These metabolites, which were identified by nuclear magnetic resonance and mass spectrometric analysis, accumulate after a 1 week growth period. BAS 3191 (60 μmol/1.) was transformed into 23 μmol/1. of M-l and 12 μmol/1. of M-2, respectively.

UR - http://www.scopus.com/inward/record.url?scp=0015257435&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015257435&partnerID=8YFLogxK

U2 - 10.1021/jf60179a027

DO - 10.1021/jf60179a027

M3 - Article

C2 - 5059938

AN - SCOPUS:0015257435

SN - 0021-8561

VL - 20

SP - 20

EP - 22

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

IS - 1

ER -

Metabolism of the Systemic Fungicide 2,5-Dimethyl-3-furancarboxylic Acid Anilide (BAS 3191) by Rhizopus japonicus and Related Fungi

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this