TY - JOUR
T1 - Metabolic Effects of Endoscopic Duodenal Mucosal Resurfacing
T2 - a Systematic Review and Meta-analysis
AU - de Oliveira, Guilherme Henrique Peixoto
AU - de Moura, Diogo Turiani Hourneaux
AU - Funari, Mateus Pereira
AU - McCarty, Thomas R.
AU - Ribeiro, Igor Braga
AU - Bernardo, Wanderley Marques
AU - Sagae, Vitor Massaro Takamatsu
AU - Freitas, João Remi
AU - Souza, Gabriel Mayo de Vieira
AU - de Moura, Eduardo Guimarães Hourneaux
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.
PY - 2021/3
Y1 - 2021/3
N2 - Duodenal mucosal resurfacing (DMR) is an innovative endoscopic bariatric and metabolic therapy (EBMT) emerging in recent years. It uses the duodenum to achieve better glycemic and weight control. This study aimed to evaluate in a critical and systematic way the metabolic effects of this procedure. Electronic searches were performed evaluating the DMR procedure based on predefined inclusion and exclusion criteria. Changes in measured outcomes were evaluated using random-effects models by computing weighted mean differences (MD) and corresponding 95% CIs between pre-and post-procedure metabolic characteristics. Four studies were selected for qualitative and quantitative analysis. DMR demonstrated beneficial glycemic and hepatic metabolic effects among patients with non-insulin dependent type 2 diabetes (T2D) at 3 and 6 months post-procedure.
AB - Duodenal mucosal resurfacing (DMR) is an innovative endoscopic bariatric and metabolic therapy (EBMT) emerging in recent years. It uses the duodenum to achieve better glycemic and weight control. This study aimed to evaluate in a critical and systematic way the metabolic effects of this procedure. Electronic searches were performed evaluating the DMR procedure based on predefined inclusion and exclusion criteria. Changes in measured outcomes were evaluated using random-effects models by computing weighted mean differences (MD) and corresponding 95% CIs between pre-and post-procedure metabolic characteristics. Four studies were selected for qualitative and quantitative analysis. DMR demonstrated beneficial glycemic and hepatic metabolic effects among patients with non-insulin dependent type 2 diabetes (T2D) at 3 and 6 months post-procedure.
KW - Diabetes
KW - DMR
KW - Duodenal mucosal resurfacing
KW - Hepatic steatosis
KW - Hydrothermal ablation
KW - Systematic review
UR - http://www.scopus.com/inward/record.url?scp=85099251948&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85099251948&partnerID=8YFLogxK
U2 - 10.1007/s11695-020-05170-3
DO - 10.1007/s11695-020-05170-3
M3 - Review article
C2 - 33417100
AN - SCOPUS:85099251948
SN - 0960-8923
VL - 31
SP - 1304
EP - 1312
JO - Obesity Surgery
JF - Obesity Surgery
IS - 3
ER -