Metabolic control of proteasome function

Fengxue Zhang; Andrew J. Paterson; Ping Huang; Kai Wang; Jeffrey E. Kudlow

doi:10.1152/physiol.00026.2007

Metabolic control of proteasome function

Fengxue Zhang, Andrew J. Paterson, Ping Huang, Kai Wang, Jeffrey E. Kudlow

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

Proteasomes are major cellular proteases that are important for protein turnover and cell survival. Dysregulation of proteasome is related to many major human diseases. Regulation of the proteasome is beginning to be understood by the recent findings that proteasomes are modified and regulated by metabolic factors O-GlcNAcylation and PKA phosphorylation.

Original language	English (US)
Pages (from-to)	373-379
Number of pages	7
Journal	Physiology
Volume	22
Issue number	6
DOIs	https://doi.org/10.1152/physiol.00026.2007
State	Published - Dec 2007

ASJC Scopus subject areas

Physiology

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10.1152/physiol.00026.2007

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@article{a6485fe69bd8440fa177ce162fc36c48,

title = "Metabolic control of proteasome function",

abstract = "Proteasomes are major cellular proteases that are important for protein turnover and cell survival. Dysregulation of proteasome is related to many major human diseases. Regulation of the proteasome is beginning to be understood by the recent findings that proteasomes are modified and regulated by metabolic factors O-GlcNAcylation and PKA phosphorylation.",

author = "Fengxue Zhang and Paterson, \{Andrew J.\} and Ping Huang and Kai Wang and Kudlow, \{Jeffrey E.\}",

year = "2007",

month = dec,

doi = "10.1152/physiol.00026.2007",

language = "English (US)",

volume = "22",

pages = "373--379",

journal = "Physiology",

issn = "1548-9213",

publisher = "American Physiological Society",

number = "6",

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T1 - Metabolic control of proteasome function

AU - Zhang, Fengxue

AU - Paterson, Andrew J.

AU - Huang, Ping

AU - Wang, Kai

AU - Kudlow, Jeffrey E.

PY - 2007/12

Y1 - 2007/12

N2 - Proteasomes are major cellular proteases that are important for protein turnover and cell survival. Dysregulation of proteasome is related to many major human diseases. Regulation of the proteasome is beginning to be understood by the recent findings that proteasomes are modified and regulated by metabolic factors O-GlcNAcylation and PKA phosphorylation.

AB - Proteasomes are major cellular proteases that are important for protein turnover and cell survival. Dysregulation of proteasome is related to many major human diseases. Regulation of the proteasome is beginning to be understood by the recent findings that proteasomes are modified and regulated by metabolic factors O-GlcNAcylation and PKA phosphorylation.

UR - https://www.scopus.com/pages/publications/37149047542

UR - https://www.scopus.com/inward/citedby.url?scp=37149047542&partnerID=8YFLogxK

U2 - 10.1152/physiol.00026.2007

DO - 10.1152/physiol.00026.2007

M3 - Review article

C2 - 18073410

AN - SCOPUS:37149047542

SN - 1548-9213

VL - 22

SP - 373

EP - 379

JO - Physiology

JF - Physiology

IS - 6

ER -

Metabolic control of proteasome function

Abstract

ASJC Scopus subject areas

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