Abstract
Disclosed are mesoporous silicon multi-stage vehicles that comprise liposomal-based second-stage particles, as well as pharmaceutical compositions and formulations including such vectors for use in a variety of diagnostic and therapeutic indications. In particular embodiments, MSV comprising ligand decorated second-stage particles are provided for therapeutic methods including, for example, treatment of mammalian cancers, including those of the human breast.
Original language | English (US) |
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Patent number | US2013195963 |
IPC | A61K 39/ 00 A I |
Priority date | 12/7/12 |
State | Published - Aug 1 2013 |