TY - JOUR
T1 - Mercury in human hair and blood samples from people living in Wanshan mercury mine area, Guizhou, China
T2 - An XAS study
AU - Li, Yu Feng
AU - Chen, Chunying
AU - Li, Bai
AU - Li, Wei
AU - Qu, Liya
AU - Dong, Zeqin
AU - Nomura, Masaharu
AU - Gao, Yuxi
AU - Zhao, Jinxuan
AU - Hu, Wei
AU - Zhao, Yuliang
AU - Chai, Zhifang
N1 - Funding Information:
The research was financially supported by Natural Science Foundation of China (No. 10490180 and 20751001), the 973 programs (2006CB705603), Chinese Academy of Sciences Knowledge Innovation Program, International Atomic Energy Agency (CPR-13246), and the EU sixth Framework Program (FOOD-CT-2006-016253). We are grateful to Prof. Yaning Xie, Dr. Tao Liu and Dr. Dongliang Chen for their kind help and discussion for the XAFS measurement at BSRF and Dr. Yasuhiro Inada and Dr. Yoshinori Kitajima at Photon Factory. Any opinions, findings, and conclusions or recommendations expressed in this paper are those of the authors and do not necessarily reflect the views of the specific granting agency.
PY - 2008/3
Y1 - 2008/3
N2 - Human hair and blood samples from persons living in the town of Wanshan, a mercury mine area in Guizhou Province of China, were collected and the quantitative speciation and structural information of Hg and S in hair samples and of Hg in erythrocyte and serum samples were studied using X-ray absorption spectroscopy. Least-squares fitting of the X-ray absorption near-edge spectra found that inorganic mercury is the major mercury species in hair samples (91.74%), while inorganic and methyl mercury are both about 50% of total mercury in RBC and serum samples, which is in agreement with the data obtained by acidic extraction, fractionation of Hg2+ and CH3Hg+ and quantification by ICP-MS. Curve-fitting analysis revealed that the Hg-S bond length and coordination number in hair were 0.248 ± 0.002 nm and 3.10, respectively, while the S-Hg bond length and coordination number in hair were 0.236 ± 0.002 nm and 4.05. The Hg-S bond length and coordination number in RBC were 0.251 ± 0.003 nm and 4.09, respectively, while they were 0.228 ± 0.002 nm and 4.08 in serum, respectively. The techniques for speciation, structural and binding information described in this study will find the potential application in similar studies of other elements.
AB - Human hair and blood samples from persons living in the town of Wanshan, a mercury mine area in Guizhou Province of China, were collected and the quantitative speciation and structural information of Hg and S in hair samples and of Hg in erythrocyte and serum samples were studied using X-ray absorption spectroscopy. Least-squares fitting of the X-ray absorption near-edge spectra found that inorganic mercury is the major mercury species in hair samples (91.74%), while inorganic and methyl mercury are both about 50% of total mercury in RBC and serum samples, which is in agreement with the data obtained by acidic extraction, fractionation of Hg2+ and CH3Hg+ and quantification by ICP-MS. Curve-fitting analysis revealed that the Hg-S bond length and coordination number in hair were 0.248 ± 0.002 nm and 3.10, respectively, while the S-Hg bond length and coordination number in hair were 0.236 ± 0.002 nm and 4.05. The Hg-S bond length and coordination number in RBC were 0.251 ± 0.003 nm and 4.09, respectively, while they were 0.228 ± 0.002 nm and 4.08 in serum, respectively. The techniques for speciation, structural and binding information described in this study will find the potential application in similar studies of other elements.
KW - Blood
KW - Human hair
KW - Mercury exposure
KW - Speciation
KW - XAS
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U2 - 10.1016/j.jinorgbio.2007.11.005
DO - 10.1016/j.jinorgbio.2007.11.005
M3 - Article
C2 - 18166227
AN - SCOPUS:39249083594
SN - 0162-0134
VL - 102
SP - 500
EP - 506
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 3
ER -