Membranous glomerulonephritis associated with inflammatory demyelinating peripheral neuropathies

M. Panjwani, Luan Truong, G. Eknoyan

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31 Scopus citations


A 55-year-old man with chronic inflammatory demyelinating polyradiculoneuropathy developed the nephrotic syndrome. Renal biopsy showed stage I membranous glomerulonephritis. Review of the literature revealed the association of these two rare syndromes, considered to be due to immunologic dysfunction, in two other cases, as well as several cases of the acute form of demyelinating peripheral polyradiculoneuropathy. The nephrotic syndrome appears to be persistent in the chronic form of the peripheral neuropathy but reversible in its acute form following immunosuppressive therapy. The possibility of a common immunopathogenesis in the association of membranous glomerulonephritis and inflammatory demyelinating peripheral neuropathies deserves further scrutiny.

Original languageEnglish (US)
Pages (from-to)279-283
Number of pages5
JournalAmerican Journal of Kidney Diseases
Issue number2
StatePublished - 1996


  • acute inflammatory demyelinating polyradiculoneuropathy
  • chronic inflammatory demyelinating polyradiculoneuropathy
  • Guillain-Barre syndrome
  • membranous glomerulonephritis
  • Nephrotic syndrome

ASJC Scopus subject areas

  • Nephrology


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