Mediterranean diet and cognitive function: The sun project

Cecilia Galbete, E. Toledo, J. B. Toledo, M. Bes-Rastrollo, P. Buil-Cosiales, A. Marti, F. Guillén-Grima, M. A. Martínez-González

Research output: Contribution to journalArticlepeer-review

66 Scopus citations


Objective: Our aim was to evaluate the association between adherence to the Mediterranean Diet (MedDiet) and cognitive function in 823 participants (62 ± 6 years at baseline) from a Spanish prospective cohort (SUN project).

Method: A validated 136-item food frequency questionnaire was used to assess the adherence to the MedDiet at baseline. The 10-point (0 to 9) MedDiet Score was used to categorize adherence to MedDiet. Cognitive function was assessed twice at follow-up with a mean follow-up time between exposure and outcome assessment of 6 and 8y using the Telephone Interview of Cognitive Status-modified (TICS-m, range 0 to 54 points). ANCOVA models were used to assess the association between adherence to the MedDiet and cognitive decline.

Conclusion: A higher adherence to the MedDiet might be associated with better cognitive function. However, observed differences were of small magnitude and further studies are needed to confirm this finding.

Results: In the multivariable-adjusted analysis of 2-year changes, a higher cognitive decline was observed among participants with low or moderate baseline adherence to the MedDiet than among those with better adherence (adjusted difference = −0.56 points in TICS-m, 95% CI = −0.99 to −0.13).

Original languageEnglish (US)
Pages (from-to)305-312
Number of pages8
JournalJournal of Nutrition, Health and Aging
Issue number3
StatePublished - Mar 11 2015


  • cognitive function
  • Mediterranean diet
  • monounsaturated fatty acids
  • olive oil

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Geriatrics and Gerontology


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