Mechanistic Study of the Conversion of Superoxide to Oxygen and Hydrogen Peroxide in Carbon Nanoparticles

Almaz S. Jalilov; Chenhao Zhang; Errol L.G. Samuel; William K.A. Sikkema; Gang Wu; Vladimir Berka; Thomas A. Kent; Ah Lim Tsai; James M. Tour

doi:10.1021/acsami.6b03502

Mechanistic Study of the Conversion of Superoxide to Oxygen and Hydrogen Peroxide in Carbon Nanoparticles

Almaz S. Jalilov, Chenhao Zhang, Errol L.G. Samuel, William K.A. Sikkema, Gang Wu, Vladimir Berka, Thomas A. Kent, Ah Lim Tsai, James M. Tour

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Hydrophilic carbon clusters (HCCs) are oxidized carbon nanoparticles with a high affinity for electrons. The electron accepting strength of HCCs, employing the efficient conversion of superoxide (O₂^•-) to molecular oxygen (O₂) via single-electron oxidation, was monitored using cyclic voltammetry and electron paramagnetic resonance spectroscopy. We found that HCCs possess O₂ reduction reaction (ORR) capabilities through a two-electron process with the formation of H₂O₂. By comparing results from aprotic solvents to those obtained from ORR activity in aqueous media, we propose a mechanism for the origin of the antioxidant and superoxide dismutase mimetic properties of poly(ethylene glycolated) hydrophilic carbon clusters (PEG-HCCs).

Original language	English (US)
Pages (from-to)	15086-15092
Number of pages	7
Journal	ACS Applied Materials and Interfaces
Volume	8
Issue number	24
DOIs	https://doi.org/10.1021/acsami.6b03502
State	Published - Jun 22 2016

Keywords

antioxidant
carbon nanoparticles
oxidation
oxygen reduction
superoxide

ASJC Scopus subject areas

Materials Science(all)

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10.1021/acsami.6b03502

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@article{29bf2ecb0c7640d9b77f727522a087b4,

title = "Mechanistic Study of the Conversion of Superoxide to Oxygen and Hydrogen Peroxide in Carbon Nanoparticles",

abstract = "Hydrophilic carbon clusters (HCCs) are oxidized carbon nanoparticles with a high affinity for electrons. The electron accepting strength of HCCs, employing the efficient conversion of superoxide (O2•-) to molecular oxygen (O2) via single-electron oxidation, was monitored using cyclic voltammetry and electron paramagnetic resonance spectroscopy. We found that HCCs possess O2 reduction reaction (ORR) capabilities through a two-electron process with the formation of H2O2. By comparing results from aprotic solvents to those obtained from ORR activity in aqueous media, we propose a mechanism for the origin of the antioxidant and superoxide dismutase mimetic properties of poly(ethylene glycolated) hydrophilic carbon clusters (PEG-HCCs).",

keywords = "antioxidant, carbon nanoparticles, oxidation, oxygen reduction, superoxide",

author = "Jalilov, {Almaz S.} and Chenhao Zhang and Samuel, {Errol L.G.} and Sikkema, {William K.A.} and Gang Wu and Vladimir Berka and Kent, {Thomas A.} and Tsai, {Ah Lim} and Tour, {James M.}",

note = "Funding Information: We thank the NIH (Grants R01-NS094535 and R21-NS084290) and the Dunn Foundation for financial support Publisher Copyright: {\textcopyright} 2016 American Chemical Society.",

year = "2016",

month = jun,

day = "22",

doi = "10.1021/acsami.6b03502",

language = "English (US)",

volume = "8",

pages = "15086--15092",

journal = "ACS Applied Materials and Interfaces",

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T1 - Mechanistic Study of the Conversion of Superoxide to Oxygen and Hydrogen Peroxide in Carbon Nanoparticles

AU - Jalilov, Almaz S.

AU - Zhang, Chenhao

AU - Samuel, Errol L.G.

AU - Sikkema, William K.A.

AU - Wu, Gang

AU - Berka, Vladimir

AU - Kent, Thomas A.

AU - Tsai, Ah Lim

AU - Tour, James M.

PY - 2016/6/22

Y1 - 2016/6/22

N2 - Hydrophilic carbon clusters (HCCs) are oxidized carbon nanoparticles with a high affinity for electrons. The electron accepting strength of HCCs, employing the efficient conversion of superoxide (O2•-) to molecular oxygen (O2) via single-electron oxidation, was monitored using cyclic voltammetry and electron paramagnetic resonance spectroscopy. We found that HCCs possess O2 reduction reaction (ORR) capabilities through a two-electron process with the formation of H2O2. By comparing results from aprotic solvents to those obtained from ORR activity in aqueous media, we propose a mechanism for the origin of the antioxidant and superoxide dismutase mimetic properties of poly(ethylene glycolated) hydrophilic carbon clusters (PEG-HCCs).

AB - Hydrophilic carbon clusters (HCCs) are oxidized carbon nanoparticles with a high affinity for electrons. The electron accepting strength of HCCs, employing the efficient conversion of superoxide (O2•-) to molecular oxygen (O2) via single-electron oxidation, was monitored using cyclic voltammetry and electron paramagnetic resonance spectroscopy. We found that HCCs possess O2 reduction reaction (ORR) capabilities through a two-electron process with the formation of H2O2. By comparing results from aprotic solvents to those obtained from ORR activity in aqueous media, we propose a mechanism for the origin of the antioxidant and superoxide dismutase mimetic properties of poly(ethylene glycolated) hydrophilic carbon clusters (PEG-HCCs).

KW - antioxidant

KW - carbon nanoparticles

KW - oxidation

KW - oxygen reduction

KW - superoxide

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IS - 24

ER -

Mechanistic Study of the Conversion of Superoxide to Oxygen and Hydrogen Peroxide in Carbon Nanoparticles

Abstract

Keywords

ASJC Scopus subject areas

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