TY - JOUR
T1 - Mechanisms of probiosis and prebiosis
T2 - considerations for enhanced functional foods
AU - Saulnier, Delphine MA
AU - Spinler, Jennifer K.
AU - Gibson, Glenn R.
AU - Versalovic, James
N1 - Funding Information:
JV currently receives support from the National Institutes of Health (NIH) (NIDDK R01 DK065075; NCCAM R01 AT004326; NCCAM R21 AT003482), the Office of Naval Research, the Defense Advanced Research Projects Agency (DARPA), and Public Health Service Grant DK56338, which funds the Texas Medical Center Digestive Diseases Center.
PY - 2009/4
Y1 - 2009/4
N2 - The technologies of metagenomics and metabolomics are broadening our knowledge of the roles the human gut microbiota play in health and disease. For many years now, probiotics and prebiotics have been included in foods for their health benefits; however, we have only recently begun to understand their modes of action. This review highlights recent advances in deciphering the mechanisms of probiosis and prebiosis, and describes how this knowledge could be transferred to select for enhancing functional foods targeting different populations. A special focus will be given to the addition of prebiotics and probiotics in functional foods for infants and seniors.
AB - The technologies of metagenomics and metabolomics are broadening our knowledge of the roles the human gut microbiota play in health and disease. For many years now, probiotics and prebiotics have been included in foods for their health benefits; however, we have only recently begun to understand their modes of action. This review highlights recent advances in deciphering the mechanisms of probiosis and prebiosis, and describes how this knowledge could be transferred to select for enhancing functional foods targeting different populations. A special focus will be given to the addition of prebiotics and probiotics in functional foods for infants and seniors.
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U2 - 10.1016/j.copbio.2009.01.002
DO - 10.1016/j.copbio.2009.01.002
M3 - Review article
C2 - 19243931
AN - SCOPUS:66049124638
SN - 0958-1669
VL - 20
SP - 135
EP - 141
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
IS - 2
ER -