Mechanisms of obesity-induced gastrointestinal neoplasia

José O. Alemán; Leonardo H. Eusebi; Luigi Ricciardiello; Kavish Patidar; Arun J. Sanyal; Peter R. Holt

doi:10.1053/j.gastro.2013.11.051

Mechanisms of obesity-induced gastrointestinal neoplasia

José O. Alemán, Leonardo H. Eusebi, Luigi Ricciardiello, Kavish Patidar, Arun J. Sanyal, Peter R. Holt

Research output: Contribution to journal › Review article › peer-review

172 Scopus citations

Abstract

Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.

Original language	English (US)
Pages (from-to)	357-373
Number of pages	17
Journal	Gastroenterology
Volume	146
Issue number	2
DOIs	https://doi.org/10.1053/j.gastro.2013.11.051
State	Published - Feb 2014

Keywords

Colorectal Cancer
Esophageal Cancer
Gastric Cancer
Pancreatic Cancer

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1053/j.gastro.2013.11.051

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title = "Mechanisms of obesity-induced gastrointestinal neoplasia",

abstract = "Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.",

keywords = "Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer",

author = "Alem{\'a}n, \{Jos{\'e} O.\} and Eusebi, \{Leonardo H.\} and Luigi Ricciardiello and Kavish Patidar and Sanyal, \{Arun J.\} and Holt, \{Peter R.\}",

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T1 - Mechanisms of obesity-induced gastrointestinal neoplasia

AU - Alemán, José O.

AU - Eusebi, Leonardo H.

AU - Ricciardiello, Luigi

AU - Patidar, Kavish

AU - Sanyal, Arun J.

AU - Holt, Peter R.

PY - 2014/2

Y1 - 2014/2

N2 - Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.

AB - Obesity is among the fastest growing diseases worldwide; treatment is inadequate, and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. In this report, we review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.

KW - Colorectal Cancer

KW - Esophageal Cancer

KW - Gastric Cancer

KW - Pancreatic Cancer

UR - https://www.scopus.com/pages/publications/84892742096

UR - https://www.scopus.com/inward/citedby.url?scp=84892742096&partnerID=8YFLogxK

U2 - 10.1053/j.gastro.2013.11.051

DO - 10.1053/j.gastro.2013.11.051

M3 - Review article

C2 - 24315827

AN - SCOPUS:84892742096

SN - 0016-5085

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SP - 357

EP - 373

JO - Gastroenterology

JF - Gastroenterology

IS - 2

ER -

Mechanisms of obesity-induced gastrointestinal neoplasia

Abstract

Keywords

ASJC Scopus subject areas

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