Mechanism of Ap-1-mediated gene expression by select organochlorines through the p38 MAPK pathway

Keyphrases

• Activator protein-1 (AP-1) 100%
• Gene Expression 100%
• Organochlorine 100%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 100%
• Dichlorodiphenyltrichloroethane 80%
• C-Jun 60%
• C-Fos 60%
• Estrogen Receptor 40%
• Collagenase 40%
• P38 MAP Kinase 20%
• Sequential Activation 20%
• Estrogen 20%
• Mitogen-activated Protein Kinase 20%
• Cell Signaling 20%
• Wildlife 20%
• Environmental Chemicals 20%
• Organochlorine Compounds 20%
• Signaling Cascades 20%
• Expression Induction 20%
• AP-1 Complex 20%
• Phosphorylation State 20%
• Molecular Inhibitors 20%
• Pharmacological Inhibitors 20%
• JNK Phosphorylation 20%
• Health Effects 20%
• ERK Phosphorylation 20%
• Translational Activation 20%
• Organochlorine Pesticides 20%
• Complex Shift 20%
• Kinase Cascade 20%
• P38 Signaling Pathway 20%
• Dominant Negative 20%
• HEK293 20%
• Ishikawa Cells 20%
• Receptor-independent 20%

Biochemistry, Genetics and Molecular Biology

• Gene Expression 100%
• P38 Mitogen-Activated Protein Kinases 100%
• C-Fos 100%
• Estrogen Receptor 66%
• Promoter Region 66%
• extracellular signal regulated kinase 66%
• Collagenase 66%
• Signal Transduction 33%
• Phosphotransferase 33%
• Metabolite 33%
• Kinase 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Mitogen Activated Protein Kinase P38 100%
• DDT 100%
• Estrogen Receptor 50%
• Collagenase 50%
• Phosphotransferase 25%
• Environmental Chemical 25%
• Mitogen Activated Protein Kinase 25%
• Organochlorine Derivative 25%
• Dimer 25%
• Organochlorine Pesticide 25%