Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: Characterization of 6-[¹²⁵I]methyl-8-iodo-1, 3-dichlorodibenzofuran-Ah receptor complexes

Keyphrases

• Mechanism of Action 100%
• 2,3,7,8-tetrachlorodibenzo-p-dioxin 100%
• Receptor Complex 100%
• 125I 100%
• Methyl 100%
• Ah Receptor 100%
• Hepatoblastoma 37%
• H4IIE 37%
• ECell 37%
• Rat Liver 25%
• Sepharose 25%
• Velocity Sedimentation 25%
• Binding Site 12%
• Incubation 12%
• Antagonism 12%
• Stokes Radius 12%
• Dioxin Receptor 12%
• Binding Affinity 12%
• Benzo(a)pyrene 12%
• Ethoxyresorufin-O-deethylase 12%
• Aryl Hydrocarbon Hydroxylases 12%
• Apparent Molecular Weight 12%
• Salt Concentration 12%
• Elution Profile 12%
• Ligand-dependent 12%
• Sucrose Gradient 12%
• Dibenzofuran 12%
• Liver Cytosol 12%
• Scatchard Plot 12%
• Bmax 12%
• High Salt 12%
• Nuclear Extract 12%
• Dioxins 12%
• Long-Evans Rats 12%
• Radioligand 12%
• 2,3,7,8-Tetrachlorodibenzofuran 12%
• Gel Retardation Assay 12%
• Sephacryl 12%
• Saturation Binding 12%
• Co-incubation 12%
• Gel Permeation 12%
• Responsive Element 12%
• Nuclear Binding 12%
• Cytosolic Receptors 12%
• Sedimentation Analysis 12%
• Plot Analysis 12%
• Sediment Analysis 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Iodine-125 100%
• Aromatic Hydrocarbon Receptor 100%
• 2,3,7,8-Tetrachlorodibenzodioxin 100%
• 1,3,8 Trichloro 6 Methyldibenzofuran 100%
• Liver Cell Carcinoma 18%
• Sepharose 12%
• Receptor 6%
• Binding Site 6%
• Ethoxyresorufin 6%
• Benzo(a)pyrene 6%
• Unspecific Monooxygenase 6%
• Buffer 6%
• Receptor Antagonist 6%
• Dibenzofuran 6%
• Dioxins and Dioxin-Like Compounds 6%
• Long Evans Rat 6%
• Radioligand 6%
• 2,3,7,8 Tetrachlorodibenzofuran 6%
• Cytosol Receptor 6%