Abstract
We have demonstrated high-sensitivity detection of bacteria using an array of bulk micromachined resonant cantilevers. The biological sensor is a micromechanical oscillator that consists of an array of silicon-nitride cantilevers with an immobilized antibody layer on the surface of the resonator. Measured resonant frequency shift as a function of the additional cell loading was observed and correlated to the mass of the specifically bound Escherichia coli OI57:H7 cells. Deposition and subsequent detection of E. coli cells was achieved under ambient conditions.
Original language | English (US) |
---|---|
Pages (from-to) | 450-452 |
Number of pages | 3 |
Journal | Applied Physics Letters |
Volume | 77 |
Issue number | 3 |
DOIs | |
State | Published - Jul 17 2000 |
ASJC Scopus subject areas
- Physics and Astronomy (miscellaneous)