Measurement of adhesive forces between individual Staphylococcus aureus MSCRAMMs and protein-coated surfaces by use of optical tweezers

Kathryn H. Simpson, Gabriela Bowden, Magnus Höök, Bahman Anvari

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

The force required to rupture bonds between individual Staphylococcus aureus MSCRAMMs and surfaces coated with extracellular matrix molecules has been quantified by using optical tweezers. The observed binding forces between fibrinogen or fibronectin and S. aureus MSCRAMMs occurred as an approximate integer multiple of 20 or 25 pN, respectively.

Original languageEnglish (US)
Pages (from-to)2031-2035
Number of pages5
JournalJournal of bacteriology
Volume185
Issue number6
DOIs
StatePublished - Mar 2003

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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