Matched-pair analysis and dosimetric variations of two types of software for interstitial permanent brachytherapy for prostate cancer

Hiromichi Ishiyama, Ryuji Nakamura, Takefumi Satoh, Susumu Tanji, Bin S. Teh, Mineko Uemae, Shiro Baba, Kazushige Hayakawa

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to determine whether identical dosimetric results could be achieved using different planning software for permanent interstitial brachytherapy for prostate cancer. Data from 492 patients treated with brachytherapy were used for matched-pair analysis. Interplant and Variseed were used as software for ultrasound-based treatment planning. Institution, neoadjuvant hormonal therapy, prostate volume, and source strength were used for factors to match the 2 groups. The study population comprised of 126 patients with treatment planning using Interplant software and 127 matched patients using Variseed software. Dosimetric results were compared between the 2 groups. The Variseed group showed significantly higher values for dose covering 90% of prostate volume (pD90), prostate volume covered by 150% of prescription dose (pV150), and dose covering 30% of the urethra (uD30) compared with the Interplant group. Our results showed that use of different software could lead to different dosimetric results, which might affect the clinical outcomes.

Original languageEnglish (US)
Pages (from-to)84-86
Number of pages3
JournalMedical Dosimetry
Volume37
Issue number1
DOIs
StatePublished - 2012

Keywords

  • I
  • Brachytherapy
  • Intersoftware variability
  • Matched-pair
  • Prostate cancer
  • Software

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Fingerprint Dive into the research topics of 'Matched-pair analysis and dosimetric variations of two types of software for interstitial permanent brachytherapy for prostate cancer'. Together they form a unique fingerprint.

Cite this