Mapping of unconventional myosins in mouse and human

Tama Hasson, Joseph F. Skowron, Debra J. Gilbert, Karen B. Avraham, William L. Perry, William M. Bement, Blake L. Anderson, Elliott H. Sherr, Zheng Yi Chen, Lloyd A. Greene, David C. Ward, David P. Corey, Mark S. Mooseker, Neal G. Copeland, Nancy A. Jenkins

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

Myosins are molecular motors that move along filamentous actin. Seven classes of myosin are expressed in vertebrates: conventional myosin, or myosin-II, as well as the 6 unconventional myosin classes -I, -V, -VI, VII, - IX, and -X. We have mapped in mouse 22 probes encompassing all known unconventional myosins and, as a result, have identified 16 potential unconventional myosin genes. These genes include 7 myosins-I, 2 myosins-V, 1 myosin-VI, 3 myosins-VII, 2 myosins-IX, and 1 myosin-X. The map location of 5 of these genes was identified in human chromosomes by fluorescence in situ hybridization.

Original languageEnglish (US)
Pages (from-to)431-439
Number of pages9
JournalGenomics
Volume36
Issue number3
DOIs
StatePublished - Sep 15 1996

ASJC Scopus subject areas

  • Genetics

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