Managing all the genotypic knowledge: Approach to a septic patient colonized by different Enterobacteriales with unique carbapenemases

Stacy C. Park, Alexander M. Wailan, Katie E. Barry, Kasi Vegesana, Joanne Carroll, Amy J. Mathers, William R. Miller, Jose M. Munita

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The recent development of new antimicrobials active against carbapenemase-producing Enterobacteriales (CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases. Here, we present the clinical course and treatment of Raoultella planticola bacteremia in a cirrhotic patient known to be colonized with both blaKPC- and blaOXA-48-carrying organisms.

Original languageEnglish (US)
Article numbere00029-19
JournalAntimicrobial Agents and Chemotherapy
Volume63
Issue number8
DOIs
StatePublished - 2019

Keywords

  • Carbapenem-resistant Enterobacteriales (CRE)
  • Carbapenemase-producing Enterobacteriales (CPE)
  • Ceftazidime-avibactam
  • OXA-48
  • Raoultella planticola

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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