TY - JOUR
T1 - Management of adherence to prescribed medication.
AU - Insull, W.
PY - 1985
Y1 - 1985
N2 - Nonadherence is a major problem for long-term use of drugs affecting lipid metabolism. Effective programs for comprehensive management of adherence are available. Their administration and operation can be readily integrated within the usual operations of both large and small clinical trials. The programs are subject to quality control and, hence, can be administered effectively. The cost of a comprehensive adherence program is approximately 10% of the conventional cost of clinical trials, varies according to the nature and number of adherence tests, and is probably totally recovered through resultant economies. All of the elements of the adherence program can be adapted to private practice. The relative risks of nonadherence to drugs affecting lipid metabolism are estimated from analyses of four regimen characteristics.
AB - Nonadherence is a major problem for long-term use of drugs affecting lipid metabolism. Effective programs for comprehensive management of adherence are available. Their administration and operation can be readily integrated within the usual operations of both large and small clinical trials. The programs are subject to quality control and, hence, can be administered effectively. The cost of a comprehensive adherence program is approximately 10% of the conventional cost of clinical trials, varies according to the nature and number of adherence tests, and is probably totally recovered through resultant economies. All of the elements of the adherence program can be adapted to private practice. The relative risks of nonadherence to drugs affecting lipid metabolism are estimated from analyses of four regimen characteristics.
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U2 - 10.1007/978-1-4613-2459-1_26
DO - 10.1007/978-1-4613-2459-1_26
M3 - Article
C2 - 3898749
AN - SCOPUS:0021777358
SN - 0065-2598
VL - 183
SP - 349
EP - 360
JO - Advances in experimental medicine and biology
JF - Advances in experimental medicine and biology
ER -