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Magnetic force Optical Coherence Elastography at 1.5 million a-lines per second

Chen Wu, Zhaolong Han, Manmohan Singh, Chih Hao Liu, Jiasong Li, Alexander Schill, Raksha Raghunathan, Kirill V. Larin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical Coherence Elastography (OCE) has been widely used to characterize tissue elasticity. In this paper we introduce a new excitation method using magnetic force to induce shear waves in phantoms and tissues. The shear waves were imaged using an Optical Coherence Tomography system with an A-scan rate of ∼1.5 million a-lines per second and the speed of the waves were used to quantify elasticity of different concentrations of agar sampled and porcine liver. The OCE results acquired from this magnetic force excitation were compared with the mechanical compressional tests for validation. The results showed that magnetic force OCE and mechanical testing results were in good agreement, demonstrating the ability of magnetic force OCE to accurately quantify the Young's modulus of tissue.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
EditorsValery V. Tuchin, Joseph A. Izatt, James G. Fujimoto
PublisherSPIE
ISBN (Electronic)9781628419313
DOIs
StatePublished - 2016
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX - San Francisco, United States
Duration: Feb 15 2016Feb 17 2016

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9697
ISSN (Print)1605-7422

Conference

ConferenceOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX
Country/TerritoryUnited States
CitySan Francisco
Period2/15/162/17/16

Keywords

  • elasticity
  • magnetic force
  • Optical Coherence Elastography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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