Macrophage Cell Cycle

Louis Dillac, Leon El Dika, Rahim Ullah, Jacek Z. Kubiak, Malgorzata Kloc

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

Abstract

Macrophages are dynamic and plastic immune cells essential for tissue homeostasis and pathogen defense. Their cell cycle regulation is highly influenced by intrinsic and extrinsic signals facilitating rapid responses to infections and tissue damage. Dysregulation of their cell cycle leads to diseases like cancer and HIV. This chapter highlights aspects of the macrophage cell cycle crucial for the development of targeted therapies.

Original languageEnglish (US)
Title of host publicationMonocytes and Macrophages in Development, Regeneration, and Disease
PublisherSpringer Science and Business Media Deutschland GmbH
Pages119-134
Number of pages16
Volume74
DOIs
StatePublished - Oct 1 2024

Publication series

NameResults and Problems in Cell Differentiation
PublisherSpringer Verlag
ISSN (Print)0080-1844

Keywords

  • Cellular proliferation
  • Disease progression
  • Macrophage cell cycle
  • Molecular regulators
  • Plasticity
  • Animals
  • Cell Cycle/physiology
  • Humans
  • Macrophages/immunology

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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