Lymphoepitheliomalike carcinoma of the gallbladder

David L. Todd; Jae Y. Ro; Margaret L. Gulley; Alberto G. Ayala

doi:10.1177/106689699600400309

Lymphoepitheliomalike carcinoma of the gallbladder

David L. Todd, Jae Y. Ro, Margaret L. Gulley, Alberto G. Ayala

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of a lymphoepitheliomalike carcinoma arising in the gallbladder of a 60-year-old woman. The gallbladder wall was completely replaced with a tumor that extended into the adjacent liver parenchyma. The tumor was histologically and immunophenotypically indistinguishable from lymphoepithelioma of the nasopharynx, which is an undifferentiated malignant epithelial neoplasm that is histologically distinctive owing to a prominent reactive lymphoid infiltrate. It is believed that the Epstein-Barr virus may play a role in the pathogenesis of nasopharyngeal lymphoepitheliomas; however, our case in the gallbladder was not associated with of Epstein-Barr virus DNA. To the best of our knowledge, this is the first published case of a lymphoepitheliomalike carcinoma of the gallbladder.

Original language	English (US)
Pages (from-to)	183-188
Number of pages	6
Journal	International Journal of Surgical Pathology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1177/106689699600400309
State	Published - Jan 1997

Keywords

Epstein-Barr virus
Gallbladder
Lymphoepithelioma

ASJC Scopus subject areas

Anatomy
Pathology and Forensic Medicine
Surgery

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10.1177/106689699600400309

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title = "Lymphoepitheliomalike carcinoma of the gallbladder",

abstract = "We report a case of a lymphoepitheliomalike carcinoma arising in the gallbladder of a 60-year-old woman. The gallbladder wall was completely replaced with a tumor that extended into the adjacent liver parenchyma. The tumor was histologically and immunophenotypically indistinguishable from lymphoepithelioma of the nasopharynx, which is an undifferentiated malignant epithelial neoplasm that is histologically distinctive owing to a prominent reactive lymphoid infiltrate. It is believed that the Epstein-Barr virus may play a role in the pathogenesis of nasopharyngeal lymphoepitheliomas; however, our case in the gallbladder was not associated with of Epstein-Barr virus DNA. To the best of our knowledge, this is the first published case of a lymphoepitheliomalike carcinoma of the gallbladder.",

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AU - Ro, Jae Y.

AU - Gulley, Margaret L.

AU - Ayala, Alberto G.

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N2 - We report a case of a lymphoepitheliomalike carcinoma arising in the gallbladder of a 60-year-old woman. The gallbladder wall was completely replaced with a tumor that extended into the adjacent liver parenchyma. The tumor was histologically and immunophenotypically indistinguishable from lymphoepithelioma of the nasopharynx, which is an undifferentiated malignant epithelial neoplasm that is histologically distinctive owing to a prominent reactive lymphoid infiltrate. It is believed that the Epstein-Barr virus may play a role in the pathogenesis of nasopharyngeal lymphoepitheliomas; however, our case in the gallbladder was not associated with of Epstein-Barr virus DNA. To the best of our knowledge, this is the first published case of a lymphoepitheliomalike carcinoma of the gallbladder.

AB - We report a case of a lymphoepitheliomalike carcinoma arising in the gallbladder of a 60-year-old woman. The gallbladder wall was completely replaced with a tumor that extended into the adjacent liver parenchyma. The tumor was histologically and immunophenotypically indistinguishable from lymphoepithelioma of the nasopharynx, which is an undifferentiated malignant epithelial neoplasm that is histologically distinctive owing to a prominent reactive lymphoid infiltrate. It is believed that the Epstein-Barr virus may play a role in the pathogenesis of nasopharyngeal lymphoepitheliomas; however, our case in the gallbladder was not associated with of Epstein-Barr virus DNA. To the best of our knowledge, this is the first published case of a lymphoepitheliomalike carcinoma of the gallbladder.

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Lymphoepitheliomalike carcinoma of the gallbladder

Abstract

Keywords

ASJC Scopus subject areas

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